SYNC (syncoilin, intermediate filament protein)

2014-11-01  

Identity

HGNC
SYNC
LOCATION
1p35.1
LOCUSID
81493
ALIAS
SYNC1,SYNCOILIN

Other Information

Locus ID:

NCBI: 81493
MIM: 611750
HGNC: 28897
Ensembl: ENSG00000162520

Variants:

dbSNP: 81493
ClinVar: 81493
TCGA: ENSG00000162520
COSMIC: SYNC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162520ENST00000373484Q9H7C4
ENSG00000162520ENST00000409190Q9H7C4
ENSG00000162520ENST00000417633C9JSS1
ENSG00000162520ENST00000426909C9JTN4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
337348922021Elevated SYNC Expression Is Associated with Gastric Tumorigenesis and Infiltration of M2-Polarized Macrophages in the Gastric Tumor Immune Microenvironment.1
337348922021Elevated SYNC Expression Is Associated with Gastric Tumorigenesis and Infiltration of M2-Polarized Macrophages in the Gastric Tumor Immune Microenvironment.1
201992072010Dysbindin, syncoilin, and beta-synemin mRNA levels in dystrophic muscles.2
205875922010Syncoilin modulates peripherin filament networks and is necessary for large-calibre motor neurons.13
201992072010Dysbindin, syncoilin, and beta-synemin mRNA levels in dystrophic muscles.2
205875922010Syncoilin modulates peripherin filament networks and is necessary for large-calibre motor neurons.13
161240042005Syncoilin upregulation in muscle of patients with neuromuscular disease.9
161240042005Syncoilin upregulation in muscle of patients with neuromuscular disease.9

Citation

Dessen P

SYNC (syncoilin, intermediate filament protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74408