TMEM47 (transmembrane protein 47)

2014-11-01  

Identity

HGNC
TMEM47
LOCATION
Xp21.1
LOCUSID
83604
ALIAS
BCMP1,TM4SF10,VAB-9

Other Information

Locus ID:

NCBI: 83604
MIM: 300698
HGNC: 18515
Ensembl: ENSG00000147027

Variants:

dbSNP: 83604
ClinVar: 83604
TCGA: ENSG00000147027
COSMIC: TMEM47

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147027ENST00000275954Q9BQJ4
ENSG00000147027ENST00000275954A0A024RBY7

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
337453902021Overexpression of TMEM47 Induces Tamoxifen Resistance in Human Breast Cancer Cells.2
337453902021Overexpression of TMEM47 Induces Tamoxifen Resistance in Human Breast Cancer Cells.2
326941682020TMEM147 interacts with lamin B receptor, regulates its localization and levels, and affects cholesterol homeostasis.10
329453732020Clinical significance and functional role of transmembrane protein 47 (TMEM47) in chemoresistance of hepatocellular carcinoma.6
326941682020TMEM147 interacts with lamin B receptor, regulates its localization and levels, and affects cholesterol homeostasis.10
329453732020Clinical significance and functional role of transmembrane protein 47 (TMEM47) in chemoresistance of hepatocellular carcinoma.6
218810012011TM4SF10 and ADAP interaction in podocytes: role in Fyn activity and nephrin phosphorylation.8
218810012011TM4SF10 and ADAP interaction in podocytes: role in Fyn activity and nephrin phosphorylation.8
153450282004TM4SF10 gene sequencing in XLMR patients identifies common polymorphisms but no disease-associated mutation.4
153450282004TM4SF10 gene sequencing in XLMR patients identifies common polymorphisms but no disease-associated mutation.4
114726332001Identification of the gene encoding Brain Cell Membrane Protein 1 (BCMP1), a putative four-transmembrane protein distantly related to the Peripheral Myelin Protein 22 / Epithelial Membrane Proteins and the Claudins.17
114726332001Identification of the gene encoding Brain Cell Membrane Protein 1 (BCMP1), a putative four-transmembrane protein distantly related to the Peripheral Myelin Protein 22 / Epithelial Membrane Proteins and the Claudins.17

Citation

Dessen P

TMEM47 (transmembrane protein 47)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74949