TMPRSS9 (transmembrane serine protease 9)

2014-11-01  

Identity

HGNC
TMPRSS9
LOCATION
19p13.3
LOCUSID
360200
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 360200
MIM: 610477
HGNC: 30079
Ensembl: ENSG00000178297

Variants:

dbSNP: 360200
ClinVar: 360200
TCGA: ENSG00000178297
COSMIC: TMPRSS9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178297ENST00000332578Q7Z410
ENSG00000178297ENST00000613480A0A0C4DGY1
ENSG00000178297ENST00000648592A0A3B3IU58
ENSG00000178297ENST00000649857Q7Z410

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
319430162020Combination of whole exome sequencing and animal modeling identifies TMPRSS9 as a candidate gene for autism spectrum disorder.2
319430162020Combination of whole exome sequencing and animal modeling identifies TMPRSS9 as a candidate gene for autism spectrum disorder.2
247566972014Polyserase-1/TMPRSS9 induces pro-tumor effects in pancreatic cancer cells by activation of pro-uPA.4
247566972014Polyserase-1/TMPRSS9 induces pro-tumor effects in pancreatic cancer cells by activation of pro-uPA.4
232298372013TMPRSS9 and GRIN2B are associated with neuroticism: a genome-wide association study in a European sample.10
232298372013TMPRSS9 and GRIN2B are associated with neuroticism: a genome-wide association study in a European sample.10
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
168722792006Serase-1B, a new splice variant of polyserase-1/TMPRSS9, activates urokinase-type plasminogen activator and the proteolytic activation is negatively regulated by glycosaminoglycans.8
168722792006Serase-1B, a new splice variant of polyserase-1/TMPRSS9, activates urokinase-type plasminogen activator and the proteolytic activation is negatively regulated by glycosaminoglycans.8
128860142003Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product.24
128860142003Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product.24

Citation

Dessen P

TMPRSS9 (transmembrane serine protease 9)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75018