ZNF175 (zinc finger protein 175)

2014-11-01  

Identity

HGNC
ZNF175
LOCATION
19q13.41
LOCUSID
7728
ALIAS
OTK18
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7728
MIM: 601139
HGNC: 12964
Ensembl: ENSG00000105497

Variants:

dbSNP: 7728
ClinVar: 7728
TCGA: ENSG00000105497
COSMIC: ZNF175

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105497ENST00000262259Q9Y473
ENSG00000105497ENST00000436511G3V1K8
ENSG00000105497ENST00000545217F5GZI7
ENSG00000105497ENST00000596504M0R013

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
190346692009Calpain and proteasomal regulation of antiretroviral zinc finger protein OTK18 in human macrophages: visualization in live cells by intramolecular FRET.2
190346702009YY1 and FoxD3 regulate antiretroviral zinc finger protein OTK18 promoter activation induced by HIV-1 infection.5
192477252009The effect of OTK18 upregulation in U937 cells on neuronal survival.2
190346692009Calpain and proteasomal regulation of antiretroviral zinc finger protein OTK18 in human macrophages: visualization in live cells by intramolecular FRET.2
190346702009YY1 and FoxD3 regulate antiretroviral zinc finger protein OTK18 promoter activation induced by HIV-1 infection.5
192477252009The effect of OTK18 upregulation in U937 cells on neuronal survival.2
187732972008OTK18 levels in plasma and cerebrospinal fluid correlate with viral load and CD8 T-cells in normal and AIDS patients.4
187766382008Characterization of gene expression regulated by human OTK18 using Drosophila melanogaster as a model system for innate immunity.0
187732972008OTK18 levels in plasma and cerebrospinal fluid correlate with viral load and CD8 T-cells in normal and AIDS patients.4
187766382008Characterization of gene expression regulated by human OTK18 using Drosophila melanogaster as a model system for innate immunity.0
146883462004Molecular characterization of a putative antiretroviral transcriptional factor, OTK18.16
150812642004OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis.10
146883462004Molecular characterization of a putative antiretroviral transcriptional factor, OTK18.16

Citation

Dessen P

ZNF175 (zinc finger protein 175)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/76009/favicon/css/template-card.css