BCAR3 (BCAR3 adaptor protein, NSP family member)

2003-06-01  

Identity

HGNC
BCAR3
LOCATION
1p22.1
LOCUSID
8412
ALIAS
AND-34,MIG7,NSP2,SH2D3B
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8412
MIM: 604704
HGNC: 973
Ensembl: ENSG00000137936

Variants:

dbSNP: 8412
ClinVar: 8412
TCGA: ENSG00000137936
COSMIC: BCAR3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137936ENST00000260502O75815
ENSG00000137936ENST00000260502A0A384MTS3
ENSG00000137936ENST00000370243O75815
ENSG00000137936ENST00000370243A0A384MTS3
ENSG00000137936ENST00000370244O75815
ENSG00000137936ENST00000370244A0A384MTS3
ENSG00000137936ENST00000370247O75815
ENSG00000137936ENST00000539242O75815

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
380630952023CircBCAR3 sponges miR-27a-3p and mediates ferroptosis in human B-prolymphocytic leukaemia cells via SLC7A11.0
380630952023CircBCAR3 sponges miR-27a-3p and mediates ferroptosis in human B-prolymphocytic leukaemia cells via SLC7A11.0
350319022022Comprehensive immunohistochemical analysis of RET, BCAR1, and BCAR3 expression in patients with Luminal A and B breast cancer subtypes.1
350319022022Comprehensive immunohistochemical analysis of RET, BCAR1, and BCAR3 expression in patients with Luminal A and B breast cancer subtypes.1
341698352021A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics.4
341698352021A Cas-BCAR3 co-regulatory circuit controls lamellipodia dynamics.4
311404212019[Mig-7 gene silencing inhibits vasculogenic mimicry formation and invasion of glioma U251 cells in vitro by suppressing MEK/ERK signaling].2
312337722019MicroRNA-126-5p downregulates BCAR3 expression to promote cell migration and invasion in endometriosis.21
316884182019Silencing of Mig-7 expression inhibits in-vitro invasiveness and vasculogenic mimicry of human glioma U87 Cells.3
311404212019[Mig-7 gene silencing inhibits vasculogenic mimicry formation and invasion of glioma U251 cells in vitro by suppressing MEK/ERK signaling].2
312337722019MicroRNA-126-5p downregulates BCAR3 expression to promote cell migration and invasion in endometriosis.21
316884182019Silencing of Mig-7 expression inhibits in-vitro invasiveness and vasculogenic mimicry of human glioma U87 Cells.3
292513182018MIG7 is involved in vasculogenic mimicry formation rendering invasion and metastasis in hepatocellular carcinoma.7
297508962018Migration-inducing gene-7 independently predicts poor prognosis of human osteosarcoma and is associated with vasculogenic mimicry.10
305635702018Prediction and prognostic significance of BCAR3 expression in patients with multiple myeloma.8

Citation

Dessen P

BCAR3 (BCAR3 adaptor protein, NSP family member)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/763/gene-fusions-explorer/case-report-explorer/img/logo-atlas-4.svg