ZNF804A (zinc finger protein 804A)

2014-11-01  

Identity

HGNC
ZNF804A
LOCATION
2q32.1
LOCUSID
91752
ALIAS
C2orf10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 91752
MIM: 612282
HGNC: 21711
Ensembl: ENSG00000170396

Variants:

dbSNP: 91752
ClinVar: 91752
TCGA: ENSG00000170396
COSMIC: ZNF804A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170396ENST00000302277Q7Z570
ENSG00000170396ENST00000613975A0A087X014

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA447199Bipolar DisorderDiseaseClinicalAnnotationassociatedPD29121268
PA447216SchizophreniaDiseaseClinicalAnnotationassociatedPD21892778
PA450243lithiumChemicalClinicalAnnotationassociatedPD29121268
PA452233antipsychoticsChemicalClinicalAnnotationassociatedPD21892778

References

Pubmed IDYearTitleCitations
382160652024Impulsivity and aggression in alcohol withdrawal syndrome is modulated by the interaction of ZNF804A and mTOR polymorphism.0
382796112024Schizophrenia risk proteins ZNF804A and NT5C2 interact in cortical neurons.1
387026952024ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic interaction for emotional and behavioral symptoms of alcohol withdrawal syndrome.0
382160652024Impulsivity and aggression in alcohol withdrawal syndrome is modulated by the interaction of ZNF804A and mTOR polymorphism.0
382796112024Schizophrenia risk proteins ZNF804A and NT5C2 interact in cortical neurons.1
387026952024ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic interaction for emotional and behavioral symptoms of alcohol withdrawal syndrome.0
337123772023Polymorphism in the ZNF804A Gene and Variation in D(1) and D(2)/D(3) Dopamine Receptor Availability in the Healthy Human Brain: A Dual Positron Emission Tomography Study.2
345245812023Impact on the Risk and Severity of Childhood Onset Schizophrenia of Schizophrenia Risk Genetic Variants at the DRD2 and ZNF804A Loci.3
357862022023Impact of ZNF804A rs1344706 or CACNA1C rs1006737 polymorphisms on cognition in patients with severe mental disorders: A systematic review and meta-analysis.3
337123772023Polymorphism in the ZNF804A Gene and Variation in D(1) and D(2)/D(3) Dopamine Receptor Availability in the Healthy Human Brain: A Dual Positron Emission Tomography Study.2
345245812023Impact on the Risk and Severity of Childhood Onset Schizophrenia of Schizophrenia Risk Genetic Variants at the DRD2 and ZNF804A Loci.3
357862022023Impact of ZNF804A rs1344706 or CACNA1C rs1006737 polymorphisms on cognition in patients with severe mental disorders: A systematic review and meta-analysis.3
319949082022The expression of zinc finger 804a (ZNF804a) and cyclin-dependent kinase 1 (CDK1) genes is related to the pathogenesis of rheumatoid arthritis.4
354472332022Genetic analysis of the ZNF804A gene in Mexican patients with schizophrenia, schizoaffective disorder and bipolar disorder.0
357284552022Study of a functional SNP rs13423388 in a novel enhancer element of schizophrenia-associated ZNF804A.0

Citation

Dessen P

ZNF804A (zinc finger protein 804A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/76416/cancer-prone-explorer/deep-insight-explorer/