ZYG11B (zyg-11 family member B, cell cycle regulator)

2014-11-01  

Identity

HGNC
ZYG11B
LOCATION
1p32.3
LOCUSID
79699
ALIAS
ZYG11
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79699
MIM: 618673
HGNC: 25820
Ensembl: ENSG00000162378

Variants:

dbSNP: 79699
ClinVar: 79699
TCGA: ENSG00000162378
COSMIC: ZYG11B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162378ENST00000294353Q9C0D3
ENSG00000162378ENST00000545132A8DPD7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
368470712023LncRNA LINC01871 sponging miR-142-3p to modulate ZYG11B promotes the chemoresistance of colorectal cancer cells by inducing autophagy.2
368470712023LncRNA LINC01871 sponging miR-142-3p to modulate ZYG11B promotes the chemoresistance of colorectal cancer cells by inducing autophagy.2
356362502022Structural insights into ORF10 recognition by ZYG11B.3
356958912022A close shave: How SARS-CoV-2 induces the loss of cilia.1
356362502022Structural insights into ORF10 recognition by ZYG11B.3
356958912022A close shave: How SARS-CoV-2 induces the loss of cilia.1
338279882021ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection.19
342144662021Molecular basis for recognition of Gly/N-degrons by CRL2(ZYG11B) and CRL2(ZER1).11
338279882021ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection.19
342144662021Molecular basis for recognition of Gly/N-degrons by CRL2(ZYG11B) and CRL2(ZER1).11
327380322020Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS.12
327380322020Functional and genetic analyses of ZYG11B provide evidences for its involvement in OAVS.12
278109092016The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage.17
278109092016The ubiquitin ligase CRL2ZYG11 targets cyclin B1 for degradation in a conserved pathway that facilitates mitotic slippage.17

Citation

Dessen P

ZYG11B (zyg-11 family member B, cell cycle regulator)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/76518