LINS1 (lines homolog 1)

2015-09-01  

Identity

HGNC
LINS1
LOCATION
15q26.3
LOCUSID
55180
ALIAS
LINS,MRT27,WINS1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55180
MIM: 610350
HGNC: 30922
Ensembl: ENSG00000140471

Variants:

dbSNP: 55180
ClinVar: 55180
TCGA: ENSG00000140471
COSMIC: LINS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140471ENST00000314742Q8NG48
ENSG00000140471ENST00000559577H0YMK4
ENSG00000140471ENST00000559736H0YKU3
ENSG00000140471ENST00000560133H3BNM9
ENSG00000140471ENST00000560272H0YM78
ENSG00000140471ENST00000560783S4R3B7
ENSG00000140471ENST00000560934H0YMQ0
ENSG00000140471ENST00000560941H3BNS6
ENSG00000140471ENST00000561308Q8NG48

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
344503472021Identification of a novel nonsense homozygous mutation of LINS1 gene in two sisters with intellectual disability, schizophrenia, and anxiety.3
344503472021Identification of a novel nonsense homozygous mutation of LINS1 gene in two sisters with intellectual disability, schizophrenia, and anxiety.3
319225982020[Identification of LINS1 gene variant in a patient with severe mental retardation].1
319225982020[Identification of LINS1 gene variant in a patient with severe mental retardation].1
237736602013LINS, a modulator of the WNT signaling pathway, is involved in human cognition.12
237736602013LINS, a modulator of the WNT signaling pathway, is involved in human cognition.12
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
121195512002Molecular cloning and characterization of human WINS1 and mouse Wins2, homologous to Drosophila segment polarity gene Lines (Lin).4
121195512002Molecular cloning and characterization of human WINS1 and mouse Wins2, homologous to Drosophila segment polarity gene Lines (Lin).4

Citation

Dessen P

LINS1 (lines homolog 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-09-01

Online version: http://atlasgeneticsoncology.org/gene/77739