TRIM58 (tripartite motif containing 58)

2003-12-01  

Identity

HGNC
LOCATION
1q44
LOCUSID
ALIAS
BIA2
FUSION GENES

Other Information

Locus ID:

NCBI: 25893
HGNC: 24150
Ensembl: ENSG00000162722

Variants:

dbSNP: 25893
ClinVar: 25893
TCGA: ENSG00000162722
COSMIC: TRIM58

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162722ENST00000366481Q8NG06

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366446092023TRIM58 Interacts with ZEB1 to Suppress NSCLC Tumor Malignancy by Promoting ZEB1 Protein Degradation via UPP.2
375168542023TRIM58 functions as a tumor suppressor in colorectal cancer by promoting RECQL4 ubiquitination to inhibit the AKT signaling pathway.0
366446092023TRIM58 Interacts with ZEB1 to Suppress NSCLC Tumor Malignancy by Promoting ZEB1 Protein Degradation via UPP.2
375168542023TRIM58 functions as a tumor suppressor in colorectal cancer by promoting RECQL4 ubiquitination to inhibit the AKT signaling pathway.0
362082352022[Correlation between the Promoter Methylation Status of TRIM58 and Its mRNA Expression in Acute Myeloid Leukemia].0
362082352022[Correlation between the Promoter Methylation Status of TRIM58 and Its mRNA Expression in Acute Myeloid Leukemia].0
334069032021TRIM58 is a prognostic biomarker remodeling the tumor microenvironment in KRAS-driven lung adenocarcinoma.6
334069032021TRIM58 is a prognostic biomarker remodeling the tumor microenvironment in KRAS-driven lung adenocarcinoma.6
317478562020TRIM58 suppresses the tumor growth in gastric cancer by inactivation of β-catenin signaling via ubiquitination.15
322191442020TRIM58 Interacts with Pyruvate Kinase M2 to Inhibit Tumorigenicity in Human Osteosarcoma Cells.15
317478562020TRIM58 suppresses the tumor growth in gastric cancer by inactivation of β-catenin signaling via ubiquitination.15
322191442020TRIM58 Interacts with Pyruvate Kinase M2 to Inhibit Tumorigenicity in Human Osteosarcoma Cells.15
313837412019TRIM58 Restrains Intestinal Mucosal Inflammation by Negatively Regulating TLR2 in Myeloid Cells.5
313837412019TRIM58 Restrains Intestinal Mucosal Inflammation by Negatively Regulating TLR2 in Myeloid Cells.5
297495382018TRIM58/cg26157385 methylation is associated with eight prognostic genes in lung squamous cell carcinoma.23

Citation

Dessen P

TRIM58 (tripartite motif containing 58)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/790/trim58