INTS13 (integrator complex subunit 13)

2017-09-01  

Identity

HGNC
INTS13
LOCATION
12p11.23
LOCUSID
55726
ALIAS
ASUN,C12orf11,GCT1,Mat89Bb,NET48,SPATA30

Other Information

Locus ID:

NCBI: 55726
MIM: 615079
HGNC: 20174
Ensembl: ENSG00000064102

Variants:

dbSNP: 55726
ClinVar: 55726
TCGA: ENSG00000064102
COSMIC: INTS13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000064102ENST00000261191Q9NVM9
ENSG00000064102ENST00000536232H0YIA9
ENSG00000064102ENST00000537336F5H5W1
ENSG00000064102ENST00000538155H0YH12
ENSG00000064102ENST00000538727F8VRX9
ENSG00000064102ENST00000544548F5H457

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
362294312022INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.9
362294312022INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.9
326472232020INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.28
326472232020INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.28
239042672013Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.16
239042672013Nuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complex.16
230974942012Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry.14
230974942012Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry.14

Citation

Dessen P

INTS13 (integrator complex subunit 13)

Atlas Genet Cytogenet Oncol Haematol. 2017-09-01

Online version: http://atlasgeneticsoncology.org/gene/79970/css/lib/dataTables.bootstrap.min.css