HASPIN (histone H3 associated protein kinase)

2017-09-01  

Identity

HGNC
HASPIN
LOCATION
17p13.2
LOCUSID
83903
ALIAS
GSG2

Other Information

Locus ID:

NCBI: 83903
MIM: 609240
HGNC: 19682
Ensembl: ENSG00000177602

Variants:

dbSNP: 83903
ClinVar: 83903
TCGA: ENSG00000177602
COSMIC: HASPIN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177602ENST00000325418Q8TF76

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384415462024GSG2 promotes thyroid cancer via stabilizing AURKB and activating AKT pathway.1
386135882024Germ cell-specific gene 2 accelerates cell cycle in epithelial ovarian cancer by inhibiting GSK3α-p27 cascade.0
387593672024GSG2 promotes progression of human endometrial cancer by regulating PD-1/PD-L1 expression via PI3K-AKT pathway.0
384415462024GSG2 promotes thyroid cancer via stabilizing AURKB and activating AKT pathway.1
386135882024Germ cell-specific gene 2 accelerates cell cycle in epithelial ovarian cancer by inhibiting GSK3α-p27 cascade.0
387593672024GSG2 promotes progression of human endometrial cancer by regulating PD-1/PD-L1 expression via PI3K-AKT pathway.0
359391162023Effects and mechanisms of GSG2 in esophageal cancer progression.1
359728872023Knockdown of GSG2 inhibits the development and progression of non-small cell lung cancer in vitro and in vivo.1
375376942023GSG2 facilitates the progression of human breast cancer through MDM2-mediated ubiquitination of E2F1.0
359391162023Effects and mechanisms of GSG2 in esophageal cancer progression.1
359728872023Knockdown of GSG2 inhibits the development and progression of non-small cell lung cancer in vitro and in vivo.1
375376942023GSG2 facilitates the progression of human breast cancer through MDM2-mediated ubiquitination of E2F1.0
350890752022Knockdown of GSG2 Suppresses the Progression of Colorectal Cancer Cells.1
350890752022Knockdown of GSG2 Suppresses the Progression of Colorectal Cancer Cells.1
338468012021GSG2 knockdown suppresses cholangiocarcinoma progression by regulating cell proliferation, apoptosis and migration.2

Citation

Dessen P

HASPIN (histone H3 associated protein kinase)

Atlas Genet Cytogenet Oncol Haematol. 2017-09-01

Online version: http://atlasgeneticsoncology.org/gene/80114