BLMH (bleomycin hydrolase)

2003-06-01  

Identity

HGNC
LOCATION
17q11.2
LOCUSID
ALIAS
BH,BMH
FUSION GENES

Other Information

Locus ID:

NCBI: 642
MIM: 602403
HGNC: 1059
Ensembl: ENSG00000108578

Variants:

dbSNP: 642
ClinVar: 642
TCGA: ENSG00000108578
COSMIC: BLMH

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108578ENST00000261714Q13867
ENSG00000108578ENST00000577290K7ENH5
ENSG00000108578ENST00000577623K7ESE8
ENSG00000108578ENST00000578090J3KS79
ENSG00000108578ENST00000580709K7EMJ3
ENSG00000108578ENST00000581037J3KSD8
ENSG00000108578ENST00000584603K7ES02

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
318755502019Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.13
318927082019Bleomycin hydrolase regulates the release of chemokines important for inflammation and wound healing by keratinocytes.12
318755502019Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.13
318927082019Bleomycin hydrolase regulates the release of chemokines important for inflammation and wound healing by keratinocytes.12
278782322017Involvement of bleomycin hydrolase and poly(ADP-ribose) polymerase-1 in Ubc9-mediated resistance to chemotherapy agents.3
278782322017Involvement of bleomycin hydrolase and poly(ADP-ribose) polymerase-1 in Ubc9-mediated resistance to chemotherapy agents.3
273272702016Effect of Bleomycin Hydrolase Gene Polymorphism on Late Pulmonary Complications of Treatment for Hodgkin Lymphoma.8
273272702016Effect of Bleomycin Hydrolase Gene Polymorphism on Late Pulmonary Complications of Treatment for Hodgkin Lymphoma.8
244960692014Hyperhomocysteinemia and bleomycin hydrolase modulate the expression of mouse brain proteins involved in neurodegeneration.16
246150292014Association among XRCC1, XRCC3, and BLHX gene polymorphisms and chromosome instability in lymphocytes from patients with endometriosis and ovarian cancer.10
252407842014Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of FLG gene mutations.3
244960692014Hyperhomocysteinemia and bleomycin hydrolase modulate the expression of mouse brain proteins involved in neurodegeneration.16
246150292014Association among XRCC1, XRCC3, and BLHX gene polymorphisms and chromosome instability in lymphocytes from patients with endometriosis and ovarian cancer.10
252407842014Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of FLG gene mutations.3
237086682013Cleavage of bleomycin hydrolase by caspase-3 during apoptosis.0

Citation

Dessen P

BLMH (bleomycin hydrolase)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/803/css/lib/haematological-explorer/case-report-explorer/