DELE1 (DAP3 binding cell death enhancer 1)

2018-11-01  

Identity

HGNC
DELE1
LOCATION
5q31.3
LOCUSID
9812
ALIAS
DELE,DELE1(L),KIAA0141

Other Information

Locus ID:

NCBI: 9812
MIM: 615741
HGNC: 28969
Ensembl: ENSG00000081791

Variants:

dbSNP: 9812
ClinVar: 9812
TCGA: ENSG00000081791
COSMIC: DELE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000081791ENST00000194118Q14154
ENSG00000081791ENST00000432126Q14154
ENSG00000081791ENST00000507481H0YA48
ENSG00000081791ENST00000508751D6RBI8

References

Pubmed IDYearTitleCitations
381022042024DELE1 haploinsufficiency causes resistance to mitochondrial stress-induced apoptosis in monosomy 5/del(5q) AML.1
381022042024DELE1 haploinsufficiency causes resistance to mitochondrial stress-induced apoptosis in monosomy 5/del(5q) AML.1
363826672023Death associated protein‑3 (DAP3) and DAP3 binding cell death enhancer‑1 (DELE1) in human colorectal cancer, and their impacts on clinical outcome and chemoresistance.5
365391112023DELE1 is protective for mitochondrial cardiomyopathy.6
363826672023Death associated protein‑3 (DAP3) and DAP3 binding cell death enhancer‑1 (DELE1) in human colorectal cancer, and their impacts on clinical outcome and chemoresistance.5
365391112023DELE1 is protective for mitochondrial cardiomyopathy.6
351632442022The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.12
351632442022The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.12
321327062020A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.176
321327072020Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway.230
321327062020A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.176
321327072020Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway.230
205636672010Identification of DELE, a novel DAP3-binding protein which is crucial for death receptor-mediated apoptosis induction.19
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
205636672010Identification of DELE, a novel DAP3-binding protein which is crucial for death receptor-mediated apoptosis induction.19

Citation

Dessen P

DELE1 (DAP3 binding cell death enhancer 1)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/80628/deep-insight-explorer/css/gene-explorer/