WWC2 (WW and C2 domain containing 2)

2003-05-01  

Identity

HGNC
WWC2
LOCATION
4q35.1
LOCUSID
80014
ALIAS
BOMB
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80014
HGNC: 24148
Ensembl: ENSG00000151718

Variants:

dbSNP: 80014
ClinVar: 80014
TCGA: ENSG00000151718
COSMIC: WWC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151718ENST00000403733Q6AWC2
ENSG00000151718ENST00000427431F8WET3
ENSG00000151718ENST00000438543Q6AWC2
ENSG00000151718ENST00000448232Q6AWC2
ENSG00000151718ENST00000504005Q6AWC2
ENSG00000151718ENST00000508614D6R9P8
ENSG00000151718ENST00000508747Q6AWC2
ENSG00000151718ENST00000513834Q6AWC2

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
370860902023WWC2 expression in the testis: Implications for spermatogenesis and male fertility.0
370860902023WWC2 expression in the testis: Implications for spermatogenesis and male fertility.0
326233872020miR-21-5p promotes lung adenocarcinoma cell proliferation, migration and invasion via targeting WWC2.20
326233872020miR-21-5p promotes lung adenocarcinoma cell proliferation, migration and invasion via targeting WWC2.20
288158832017WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma.13
288158832017WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma.13
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105

Citation

Dessen P

WWC2 (WW and C2 domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/825