BTG3 (BTG anti-proliferation factor 3)

2003-02-01  

Identity

HGNC
LOCATION
21q21.1
LOCUSID
ALIAS
ANA,ANA/BTG3,APRO4,TOB5,TOB55,TOFA
FUSION GENES

Other Information

Locus ID:

NCBI: 10950
MIM: 605674
HGNC: 1132
Ensembl: ENSG00000154640

Variants:

dbSNP: 10950
ClinVar: 10950
TCGA: ENSG00000154640
COSMIC: BTG3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154640ENST00000339775Q14201
ENSG00000154640ENST00000348354Q14201
ENSG00000154640ENST00000348354Q6IAU3
ENSG00000154640ENST00000457956C9JLA2

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
330515892022Long noncoding RNA CA3-AS1 suppresses gastric cancer migration and invasion by sponging miR-93-5p and targeting BTG3.9
350458002022Long non-coding RNA cancer susceptibility candidate 2 regulates the function of human fibroblast-like synoviocytes via the microRNA-18a-5p/B-cell translocation gene 3 signaling axis in rheumatoid arthritis.5
353623242022Correlation between BTG3, CASP9 and LRP4 single-nucleotide polymorphisms and susceptibility to papillary thyroid carcinoma.1
330515892022Long noncoding RNA CA3-AS1 suppresses gastric cancer migration and invasion by sponging miR-93-5p and targeting BTG3.9
350458002022Long non-coding RNA cancer susceptibility candidate 2 regulates the function of human fibroblast-like synoviocytes via the microRNA-18a-5p/B-cell translocation gene 3 signaling axis in rheumatoid arthritis.5
353623242022Correlation between BTG3, CASP9 and LRP4 single-nucleotide polymorphisms and susceptibility to papillary thyroid carcinoma.1
326209862020Hypoxia-induced downregulation of B-cell translocation gene 3 confers resistance to radiation therapy of colorectal cancer.1
333114812020Loss of the tumor suppressor BTG3 drives a pro-angiogenic tumor microenvironment through HIF-1 activation.5
326209862020Hypoxia-induced downregulation of B-cell translocation gene 3 confers resistance to radiation therapy of colorectal cancer.1
333114812020Loss of the tumor suppressor BTG3 drives a pro-angiogenic tumor microenvironment through HIF-1 activation.5
306891652019Suppression of miR-93-5p inhibits high-risk HPV-positive cervical cancer progression via targeting of BTG3.11
312610262019The long non-coding RNA HOTAIRM1 suppresses cell progression via sponging endogenous miR-17-5p/ B-cell translocation gene 3 (BTG3) axis in 5-fluorouracil resistant colorectal cancer cells.13
313870052019MicroRNA-519c-3p promotes tumor growth and metastasis of hepatocellular carcinoma by targeting BTG3.14
306891652019Suppression of miR-93-5p inhibits high-risk HPV-positive cervical cancer progression via targeting of BTG3.11
312610262019The long non-coding RNA HOTAIRM1 suppresses cell progression via sponging endogenous miR-17-5p/ B-cell translocation gene 3 (BTG3) axis in 5-fluorouracil resistant colorectal cancer cells.13

Citation

Dessen P

BTG3 (BTG anti-proliferation factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/849/cancer-prone-explorer/css/lib/meetings/