Department of Pharmacology, Institute of Biomedical Sciences of the University of São Paulo, São Paulo, Brazil; firstname.lastname@example.org; email@example.com
BUB3 is a WD40 protein that belongs to spindle mitotic checkpoint complex, which monitors the chromosome attachment to mitotic (or meiotic) fuse and prevents premature chromosome segregation. Alterations in BUB3 have been associated with chromosomal instability and aneuploidy, but their contribution for cancer development and progression are poorly understood, and appear to differ depending on the type of cancer. The present review contains data on BUB3 DNA, RNA, protein encoded and function.
Jorge Antonio Elias Godoy Carlos ; Joao Agostinho Machado-Neto
BUB3 (BUB3 mitotic checkpoint protein)
Atlas Genet Cytogenet Oncol Haematol. 2019-03-01
Online version: http://atlasgeneticsoncology.org/gene/855/bub3id855ch10q26