CRNN (cornulin)

2003-02-01  

Identity

HGNC
CRNN
LOCATION
1q21.3
LOCUSID
49860
ALIAS
C1orf10,DRC1,PDRC1,SEP53

Other Information

Locus ID:

NCBI: 49860
MIM: 611312
HGNC: 1230
Ensembl: ENSG00000143536

Variants:

dbSNP: 49860
ClinVar: 49860
TCGA: ENSG00000143536
COSMIC: CRNN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143536ENST00000271835Q9UBG3

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000
7000
8000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
385382652024Identification of Down-Expressed CRNN Associated with Cancer Progression and Poor Prognosis in Laryngeal Squamous Cell Carcinoma.0
385382652024Identification of Down-Expressed CRNN Associated with Cancer Progression and Poor Prognosis in Laryngeal Squamous Cell Carcinoma.0
300098322019Cornulin Is Induced in Psoriasis Lesions and Promotes Keratinocyte Proliferation via Phosphoinositide 3-Kinase/Akt Pathways.28
300098322019Cornulin Is Induced in Psoriasis Lesions and Promotes Keratinocyte Proliferation via Phosphoinositide 3-Kinase/Akt Pathways.28
282190682017Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis.12
282190682017Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis.12
258462772015Downregulation of CRNN gene and genomic instability at 1q21.3 in oral squamous cell carcinoma.12
258462772015Downregulation of CRNN gene and genomic instability at 1q21.3 in oral squamous cell carcinoma.12
242630082014Loss of CRNN expression is associated with advanced tumor stage and poor survival in patients with esophageal squamous cell carcinoma.6
242630082014Loss of CRNN expression is associated with advanced tumor stage and poor survival in patients with esophageal squamous cell carcinoma.6
225600862013Downregulation of cornulin in esophageal squamous cell carcinoma.14
238943502013Characterization of tumor suppressive function of cornulin in esophageal squamous cell carcinoma.16
225600862013Downregulation of cornulin in esophageal squamous cell carcinoma.14
238943502013Characterization of tumor suppressive function of cornulin in esophageal squamous cell carcinoma.16
204121172010Balance between SIRT1 and DBC1 expression is lost in breast cancer.37

Citation

Dessen P

CRNN (cornulin)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/870