Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23581
MIM: 605848
HGNC: 1502
Ensembl: ENSG00000105141
Variants:
dbSNP: 23581
ClinVar: 23581
TCGA: ENSG00000105141
COSMIC: CASP14
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000105141 | ENST00000427043 | P31944 |
| ENSG00000105141 | ENST00000427043 | B2CIS9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
| Formation of the cornified envelope | REACTOME | R-HSA-6809371 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34070382 | 2021 | Caspase-14-From Biomolecular Basics to Clinical Approach. A Review of Available Data. | 11 |
| 34070382 | 2021 | Caspase-14-From Biomolecular Basics to Clinical Approach. A Review of Available Data. | 11 |
| 28570747 | 2017 | Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients. | 13 |
| 28570747 | 2017 | Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients. | 13 |
| 25651379 | 2015 | S100A7 acts as a dual regulator in promoting proliferation and suppressing squamous differentiation through GATA-3/caspase-14 pathway in A431 cells. | 8 |
| 25651379 | 2015 | S100A7 acts as a dual regulator in promoting proliferation and suppressing squamous differentiation through GATA-3/caspase-14 pathway in A431 cells. | 8 |
| 24872419 | 2014 | Mesotrypsin and caspase-14 participate in prosaposin processing: potential relevance to epidermal permeability barrier formation. | 8 |
| 25121097 | 2014 | Caspase-14 expression impairs retinal pigment epithelium barrier function: potential role in diabetic macular edema. | 14 |
| 25315296 | 2014 | Pyrrolidone carboxylic acid levels or caspase-14 expression in the corneocytes of lesional skin correlates with clinical severity, skin barrier function and lesional inflammation in atopic dermatitis. | 17 |
| 24872419 | 2014 | Mesotrypsin and caspase-14 participate in prosaposin processing: potential relevance to epidermal permeability barrier formation. | 8 |
| 25121097 | 2014 | Caspase-14 expression impairs retinal pigment epithelium barrier function: potential role in diabetic macular edema. | 14 |
| 25315296 | 2014 | Pyrrolidone carboxylic acid levels or caspase-14 expression in the corneocytes of lesional skin correlates with clinical severity, skin barrier function and lesional inflammation in atopic dermatitis. | 17 |
| 23362869 | 2013 | Ceramides stimulate caspase-14 expression in human keratinocytes. | 11 |
| 23377137 | 2013 | Expression of caspase-14 and keratin-19 in the human epidermis and appendages during fetal skin development. | 6 |
| 23408445 | 2013 | Genetic variants of AICDA/CASP14 associated with childhood brain tumor. | 4 |
Citation
Dessen P
CASP14 (caspase 14)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/918/casp14
