Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 929
MIM: 158120
HGNC: 1628
Ensembl: ENSG00000170458
Variants:
dbSNP: 929
ClinVar: 929
TCGA: ENSG00000170458
COSMIC: CD14
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713366 | Tumor necrosis factor alpha (TNF-alpha) inhibitors | Chemical | ClinicalAnnotation | associated | PD | 24776844 | |
| PA443750 | Colitis, Ulcerative | Disease | ClinicalAnnotation | associated | PD | 24776844 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37671668 | 2024 | Homodimeric Granzyme A Opsonizes Mycobacterium tuberculosis and Inhibits Its Intracellular Growth in Human Monocytes via Toll-Like Receptor 4 and CD14. | 1 |
| 37749409 | 2024 | Decreased expression of TIGIT on CD14 + monocytes correlates with clinical features and laboratory parameters of patients with primary Sjögren's syndrome. | 1 |
| 38629742 | 2024 | Association analysis between CD14 gene polymorphisms and peri-implantitis susceptibility in a Chinese population. | 1 |
| 38661384 | 2024 | Virion-incorporated CD14 enables HIV-1 to bind LPS and initiate TLR4 signaling in immune cells. | 1 |
| 37671668 | 2024 | Homodimeric Granzyme A Opsonizes Mycobacterium tuberculosis and Inhibits Its Intracellular Growth in Human Monocytes via Toll-Like Receptor 4 and CD14. | 1 |
| 37749409 | 2024 | Decreased expression of TIGIT on CD14 + monocytes correlates with clinical features and laboratory parameters of patients with primary Sjögren's syndrome. | 1 |
| 38629742 | 2024 | Association analysis between CD14 gene polymorphisms and peri-implantitis susceptibility in a Chinese population. | 1 |
| 38661384 | 2024 | Virion-incorporated CD14 enables HIV-1 to bind LPS and initiate TLR4 signaling in immune cells. | 1 |
| 35802734 | 2023 | Soluble LPS receptor CD14 is increased in saliva of patients with geographic tongue. | 0 |
| 36697826 | 2023 | Tissue CD14(+)CD8(+) T cells reprogrammed by myeloid cells and modulated by LPS. | 12 |
| 36725909 | 2023 | Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model. | 1 |
| 36840585 | 2023 | Role of CD14 in human disease. | 7 |
| 37286630 | 2023 | Association of serum CD14 level and functional polymorphism C-159T in the promoter region of CD14 gene with allergic rhinitis. | 0 |
| 37478026 | 2023 | Increased circulating levels of MIP-1α and CD14 are associated with the presence of severe stenosis and hypoechoic plaques in patients with carotid atherosclerosis. | 1 |
| 37661484 | 2023 | Multifaceted role of CD14 in innate immunity and tissue homeostasis. | 3 |
Citation
Dessen P
CD14 (CD14 molecule)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/966/cd14
