CD69 (CD69 molecule)

2003-11-01  

Identity

HGNC
CD69
LOCATION
12p13.31
LOCUSID
969
ALIAS
AIM,BL-AC/P26,CLEC2C,EA1,GP32/28,MLR-3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 969
MIM: 107273
HGNC: 1694
Ensembl: ENSG00000110848

Variants:

dbSNP: 969
ClinVar: 969
TCGA: ENSG00000110848
COSMIC: CD69

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000110848ENST00000228434Q07108
ENSG00000110848ENST00000228434Q53ZX0
ENSG00000110848ENST00000536709B4E009

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA165292659tocilizumabChemicalClinicalAnnotationassociatedPD27339827
PA443434Arthritis, RheumatoidDiseaseClinicalAnnotationassociatedPD27339827

References

Pubmed IDYearTitleCitations
368544512023Cancer cell-derived CD69 induced under lipid and oxygen starvation promotes ovarian cancer progression through fibronectin.3
371568192023CD69 serves as a potential diagnostic and prognostic biomarker for hepatocellular carcinoma.0
377150252023The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer.3
368544512023Cancer cell-derived CD69 induced under lipid and oxygen starvation promotes ovarian cancer progression through fibronectin.3
371568192023CD69 serves as a potential diagnostic and prognostic biomarker for hepatocellular carcinoma.0
377150252023The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer.3
356909942022Combined assessment of S- and N-specific IL-2 and IL-13 secretion and CD69 neo-expression for discrimination of post-infection and post-vaccination cellular SARS-CoV-2-specific immune response.5
365187552022Machine learning links different gene patterns of viral infection to immunosuppression and immune-related biomarkers in severe burns.0
356909942022Combined assessment of S- and N-specific IL-2 and IL-13 secretion and CD69 neo-expression for discrimination of post-infection and post-vaccination cellular SARS-CoV-2-specific immune response.5
365187552022Machine learning links different gene patterns of viral infection to immunosuppression and immune-related biomarkers in severe burns.0
324083402021Apoptosis inhibitor of macrophage as a biomarker for disease activity in Japanese children with IgA nephropathy and Henoch-Schönlein purpura nephritis.6
336274052021T cells selectively filter oscillatory signals on the minutes timescale.22
343442442021Prognostic Relevance of Concordant Expression CD69 and CD56 in Response to Bortezomib Combination Therapy in Multiple Myeloma Patients.6
344276482021CD4+ T cells in inflammatory diseases: pathogenic T-helper cells and the CD69-Myl9 system.4
324083402021Apoptosis inhibitor of macrophage as a biomarker for disease activity in Japanese children with IgA nephropathy and Henoch-Schönlein purpura nephritis.6

Citation

Dessen P

CD69 (CD69 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/988/tumors-explorer/haematological-explorer/js/lib/popper.js