t(1;18)(q25;q23)

1999-09-01   Jean-Loup Huret 

1.Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France

Clinics and Pathology

Disease

acute myeloid leukemia (AML) and acute lymphocycic leukemia (ALL)

Phenotype stem cell origin

M2 and M6AML, L2-ALL

Etiology

1 case was a therapy related AML, and the 2 other cases were found in Down syndrome (DS) patients

Epidemiology

poorly known: only 3 cases to date; 3 female patients aged 1-13 yrs

Prognosis

yet unknown : cases dead at 1 mth and alive at 2 mths+ (2 DS cases), alive at 12 mths+ (therapy related case)

Bibliography

Pubmed IDLast YearTitleAuthors

Citation

Jean-Loup Huret

t(1;18)(q25;q23)

Atlas Genet Cytogenet Oncol Haematol. 1999-09-01

Online version: http://atlasgeneticsoncology.org/haematological/1162/favicon/apple-touch-icon.png