found in various hematological malignancies: 2 chronic myelogenous leukemia (CML), 1 of which in accelerated phase, 1 myelodysplastic syndrome (MDS) of RAEB type, 2 treatment related MDS, 2 M3- AML (acute myeloid leukemia), 2 acute lymphocytic leukemias (ALL), and 1 treatment related ALL, 3 non Hodgkin lymphoma (NHL), (2 follicular and 1 diffuse large cell NHL) . Five patients had a history of a previous treatment for malignancy (alkylating agent in 3 cases).

only 13 cases to date; 7 to 87 yr old patients, most patients being in the fifties; sex ratio: 7M/6F

very variable survival, from 25 days to 16 yrs+

according to the variability in the above data, the t(1;3)(p36;p21) is likely to be heterogeneous also at the molecular level.

NHL