t(1;16)(q12;q24)

2000-02-01   Jean-Loup Huret 

1.Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France

Clinics and Pathology

Disease

Acute myeloid leukemia (AML)

Note

poorly known: only 2 cases to date

Phenotype stem cell origin

a case of Fanconi anemia and a case of M1-AML

Epidemiology

The Fanconi anemia patient was a 9 yr old girl, and the AML case was a 22 yr old male patient

Prognosis

unknown

Bibliography

Pubmed IDLast YearTitleAuthors
106024181999Fluorescence in situ hybridization analysis of chromosome 1 abnormalities in hematopoietic disorders: rearrangements of DNA satellite II and new recurrent translocations.Busson-Le Coniat M et al

Summary

Atlas Image
t(1;16)(q12;q24) Fluorescence in situ hybridization with Vysis LSI 1p36/LSI 1q25 dual-color probe (Abbott molecular, US) showing extra copy of 1q25 on metaphase with der(16)t(1;16) (green signal on der(16) chromosome) u2013 Courtesy Adriana Zamecnikova.

Citation

Jean-Loup Huret

t(1;16)(q12;q24)

Atlas Genet Cytogenet Oncol Haematol. 2000-02-01

Online version: http://atlasgeneticsoncology.org/haematological/1318/t(1;16)(q12;q24)

External Links