t(2;10)(p23;p11) EPC1/ASXL2

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Adult T-cell lymphoma/leukemia (HTLV-1+)

Genes Involved and Proteins

Gene name
EPC1
Location
10p11.22
Gene name
ASXL2
Location
2p23.3

Highly cited references

Pubmed IDYearTitleCitations
237360282013Functional and cancer genomics of ASXL family members.61

Bibliography

Pubmed IDLast YearTitleAuthors
194847612009Alteration of enhancer of polycomb 1 at 10p11.2 is one of the genetic events leading to development of adult T-cell leukemia/lymphoma.Nakahata S et al

Summary

Fusion gene

EPC1/ASXL2 EPC1 (10p11.22) ASXL2 (2p23.3)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to submit at the top of the site 

Citation

Philippe Dessen ; Jean-Loup Huret

t(2;10)(p23;p11) EPC1/ASXL2

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/1663/t(2;10)(p23;p11)-epc1-asxl2