1.Department of Pathology, Peking University Peoples Hospital, Beijing 100044, Peoples Republic of China; firstname.lastname@example.org
Primary DLBCL of the central nervous system (DLBCL-CNS) is an aggressive B-cell neoplasm due in part to the intra-cerebral and/or intra-ocular location, and because a high percentage of cases are in the activated B cell like (ABC) subtype. Lymphoproliferative diseases of the central nervous system are rare, diagnostics and treatment are accordingly challenging. The special localization is related with a series of newly recognized genetic, genomic and immunologic features directing to the strong interaction between transformed lymphoma cells, neural tissue components and the local immune response. Here the clinicopathological of DLBCL-CNS will be discussed.
Primary DLBCL of the central nervous system (CNS)
Atlas Genet Cytogenet Oncol Haematol. 2017-09-01
Online version: http://atlasgeneticsoncology.org/haematological/2154/primary-dlbcl-of-the-central-nervous-system-(cns)