t(7;11)(q21;q23) CDK6/KMT2A

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes Involved and Proteins

Gene name
Location
7q21.2
Gene name
Location
11q23.3

Bibliography

Pubmed IDLast YearTitleAuthors
119300092002Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.Raffini LJ et al

Summary

Fusion gene

CDK6/KMT2A CDK6 (7q21.2) KMT2A (11q23.3)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Philippe Dessen ; Jean-Loup Huret

t(7;11)(q21;q23) CDK6/KMT2A

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2587/t(7;11)(q21;q23)-cdk6-kmt2a

External Links