t(1;2)(p32;q13) PAX8/GLIS1

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

PAX8

Location

2q14.1

Gene name

GLIS1

Location

1p32.3

Highly cited references

Pubmed IDYearTitleCitations
306489292019GLIS Rearrangement is a Genomic Hallmark of Hyalinizing Trabecular Tumor of the Thyroid Gland.18
312733142019PAX8-GLIS3 gene fusion is a pathognomonic genetic alteration of hyalinizing trabecular tumors of the thyroid.8

Bibliography

Pubmed IDLast YearTitleAuthors
255005442015The landscape and therapeutic relevance of cancer-associated transcript fusions.Yoshihara K et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(1;2)(p32;q13) PAX8/GLIS1

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/104299/t(1;2)(p32;q13)-pax8-glis1