t(5;6)(q31;p21) BRD8/PHF1

0000-00-00   Jean-Loup Huret , Philippe Dessen 

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

BRD8

Location

5q31.2

Gene name

PHF1

Location

6p21.32

Highly cited references

Pubmed IDYearTitleCitations
287582772017Fusion of the genes BRD8 and PHF1 in endometrial stromal sarcoma.16
307893592019Undifferentiated Uterine Sarcomas Represent Under-Recognized High-grade Endometrial Stromal Sarcomas.11
323177042020High-grade transformation of low-grade endometrial stromal sarcomas lacking YWHAE and BCOR genetic abnormalities.5

Bibliography

Pubmed IDLast YearTitleAuthors
287582772017Fusion of the genes BRD8 and PHF1 in endometrial stromal sarcoma.Micci F et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(5;6)(q31;p21) BRD8/PHF1

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/106785/t(5;6)(q31;p21)-brd8-phf1