Mesenchymal tumors occurring mainly in adults

2021-07-09   Paola Dal Cin 

1.Brigham and Women's Hospital , Harvard Medical School, Boston , MA (USA)

Classification

Definition

Tumors that typically arise in soft tissue are being identified with increasing frequency in the kidney, specially by molecular tools 1. They show histopathological features no different from their soft tissue counterparts. Genetic confirmations 2,3 remain essential for exclusion or confirmation when sarcomas are identified resembling those typically found in soft tissues.  Therefore, more comprehensive details will be available in the WHO 2020 Soft tissue and Bone Tumors. PAX8, which is a marker of renal epithelial tumors, is negative in renal sarcomas.

Bibliography

Reference NumberPubmed IDLast YearTitleAuthors
1257731282015Mesenchymal tumors of adult kidney.Samaratunga H et al
2109356492000Primary renal synovial sarcoma: molecular and morphologic delineation of an entity previously included among embryonal sarcomas of the kidney.Argani P et al
3111760622001Primary malignant neuroepithelial tumors of the kidney: a clinicopathologic analysis of 146 adult and pediatric cases from the National Wilms' Tumor Study Group Pathology Center.Parham DM et al

Citation

Paola Dal Cin

Mesenchymal tumors occurring mainly in adults

Atlas Genet Cytogenet Oncol Haematol. 2021-07-09

Online version: http://atlasgeneticsoncology.org/solid-tumor/208902/mesenchymal-tumors-occurring-mainly-in-adults