1.Department of Clinical Genetics, University Hospital, SE-221 85 Lund, Sweden
GLI proteins function as direct effectors of sonic hedgehog-signaling during embryogenesis. GLI1 (also GLI2 and GLI3) are therefore likely to be involved in the tissue-specific proliferation of the central nervous system, the zones of polarizing activity in the developing limb, and of the gut. In the adult human, GLI1 expression has been demonstrated in the testes, myometrium and Fallopian tubes.
Anna Dahlén ; Fredrik Mertens ; Nils Mandahl ; Ioannis Panagopoulos
Soft Tissues: Pericytoma with t(7;12)(p22;q13) ACTB/GLI1
Atlas Genet Cytogenet Oncol Haematol. 2005-03-01
Online version: http://atlasgeneticsoncology.org/solid-tumor/5192/soft-tissues-pericytoma-with-t(7;12)(p22;q13)-actb-gli1