PPP1CB (protein phosphatase 1, catalytic subunit, beta isoform)

Identity

Other names	MGC3672
	PP-1B
	PPP1CD
HGNC	PPP1CB
Location	2p23
Location_base_pair	Starts at 28828130 and ends at 28879310 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PPP1CB   9282
Entrez_Gene	PPP1CB  5500  protein phosphatase 1, catalytic subunit, beta isoform
	Cards
GeneCards	PPP1CB
Ensembl	PPP1CB [Search_View]   ENSG00000213639 [Gene_View]
Genatlas	PPP1CB
GeneLynx	PPP1CB
eGenome	PPP1CB
euGene	5500
	Genomic and cartography
GoldenPath	PPP1CB  -  2p23   chr2:28828130-28879310 +  2p23.2   [Description]    (hg18-March_2006)
Ensembl	PPP1CB - 2p23.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PPP1CB
	Gene and transcription
Genbank	AF092905 [ ENTREZ ]
Genbank	AI147919 [ ENTREZ ]
Genbank	AK312329 [ ENTREZ ]
Genbank	AM392772 [ ENTREZ ]
Genbank	BC002697 [ ENTREZ ]
RefSeq	NM_002709 [ SRS ]    NM_002709 [ ENTREZ ]
RefSeq	NM_206876 [ SRS ]    NM_206876 [ ENTREZ ]
RefSeq	AC_000045 [ SRS ]    AC_000045 [ ENTREZ ]
RefSeq	AC_000134 [ SRS ]    AC_000134 [ ENTREZ ]
RefSeq	NC_000002 [ SRS ]    NC_000002 [ ENTREZ ]
RefSeq	NT_022184 [ SRS ]    NT_022184 [ ENTREZ ]
RefSeq	NW_001838768 [ SRS ]    NW_001838768 [ ENTREZ ]
RefSeq	NW_927719 [ SRS ]    NW_927719 [ ENTREZ ]
AceView	PPP1CB AceView - NCBI
Unigene	Hs.702907 [ SRS ]    Hs.702907 [ NCBI ]     HS702907 [ spliceNest ]
	Protein : pattern, domain, 3D structure
SwissProt	P62140 [ SRS]    P62140 [ EXPASY ]     P62140 [ INTERPRO ]     P62140 [ UNIPROT ]
Prosite	PS00125 SER_THR_PHOSPHATASE [ SRS ]    PS00125 SER_THR_PHOSPHATASE [ Expasy ]
Interpro	IPR004843 M-pesterase [ SRS ]    IPR004843 M-pesterase [ EBI ]
Interpro	IPR006186 T_phtase_apaH [ SRS ]    IPR006186 T_phtase_apaH [ EBI ]
CluSTr	P62140
Pfam	PF00149 Metallophos [ SRS ]    PF00149 Metallophos [ Sanger ]    pfam00149 [ NCBI-CDD ]
Smart	SM00156 PP2Ac [EMBL]
Prodom	PD000252 T_phtase_apaH[INRA-Toulouse]
Prodom	P62140 PP1B_HUMAN [ Domain structure ]   P62140 PP1B_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P62140
PDB	1S70 [ SRS ]    1S70 [ PdbSum ],   1S70 [ IMB ]   1S70 [ RSDB ]
HPRD	11792
	Protein Interaction databases
DIP	P62140
IntAct	P62140
	Polymorphism : SNP, mutations, diseases
OMIM	600590    [ map ]
GENECLINICS	600590
SNP	PPP1CB [dbSNP-NCBI]
SNP	NM_002709 [SNP-NCI]
SNP	NM_206876 [SNP-NCI]
SNP	PPP1CB [GeneSNPs - Utah]  PPP1CB] [HGBASE - SRS]
HAPMAP	PPP1CB [HAPMAP]
COSMIC	PPP1CB [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PPP1CB
	General knowledge
Family Browser	PPP1CB [UCSC Family Browser]
SOURCE	NM_002709
SOURCE	NM_206876
SMD	Hs.702907
SAGE	Hs.702907
GO	phosphoprotein phosphatase activity [Amigo]  phosphoprotein phosphatase activity
GO	iron ion binding [Amigo]  iron ion binding
GO	protein binding [Amigo]  protein binding
GO	cytoplasm [Amigo]  cytoplasm
GO	carbohydrate metabolic process [Amigo]  carbohydrate metabolic process
GO	glycogen metabolic process [Amigo]  glycogen metabolic process
GO	protein amino acid dephosphorylation [Amigo]  protein amino acid dephosphorylation
GO	cell cycle [Amigo]  cell cycle
GO	hydrolase activity [Amigo]  hydrolase activity
GO	manganese ion binding [Amigo]  manganese ion binding
GO	metal ion binding [Amigo]  metal ion binding
GO	cell division [Amigo]  cell division
KEGG	Focal adhesion
KEGG	Long-term potentiation
KEGG	Regulation of actin cytoskeleton
KEGG	Insulin signaling pathway
PubGene	PPP1CB
TreeFam	PPP1CB
CTD	5500 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PPP1CB Related clones (RZPD - Berlin)
	PubMed
PubMed	41 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Oct 14 20:48:56 2008