| Written | 2018-01 | Jean-Loup Huret, Philippe Dessen |
| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 1628 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Diffuse large B-cell lymphoma|Follicular lymphoma |
| Genes involved and Proteins |
| Gene Name | TBL1XR1 |
| Location | 3q26.32 |
| Gene Name | TP63 |
| Location | 3q28 |
| Bibliography |
| TBL1XR1/TP63: a novel recurrent gene fusion in B-cell non-Hodgkin lymphoma |
| Scott DW, Mungall KL, Ben-Neriah S, Rogic S, Morin RD, Slack GW, Tan KL, Chan FC, Lim RS, Connors JM, Marra MA, Mungall AJ, Steidl C, Gascoyne RD |
| Blood 2012 May 24;119(21):4949-52 |
| PMID 22496164 |
| TBL1XR1/TP63: a novel recurrent gene fusion in B-cell non-Hodgkin lymphoma |
| Scott DW, Mungall KL, Ben-Neriah S, Rogic S, Morin RD, Slack GW, Tan KL, Chan FC, Lim RS, Connors JM, Marra MA, Mungall AJ, Steidl C, Gascoyne RD |
| Blood 2012 May 24;119(21):4949-52 |
| PMID 22496164 |
| Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing |
| Morin RD, Mungall K, Pleasance E, Mungall AJ, Goya R, Huff RD, Scott DW, Ding J, Roth A, Chiu R, Corbett RD, Chan FC, Mendez-Lago M, Trinh DL, Bolger-Munro M, Taylor G, Hadj Khodabakhshi A, Ben-Neriah S, Pon J, Meissner B, Woolcock B, Farnoud N, Rogic S, Lim EL, Johnson NA, Shah S, Jones S, Steidl C, Holt R, Birol I, Moore R, Connors JM, Gascoyne RD, Marra MA |
| Blood 2013 Aug 15;122(7):1256-65 |
| PMID 23699601 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| inv(3)(q26q28) TBL1XR1/TP63 | |
| External links |
| Mitelman database | inv(3)(q26q28) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Sun Jul 12 19:46:57 CEST 2020 |
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