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t(1;8)(q31;p11) TPR/FGFR1

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 1668
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Chronic myeloproliferative disorder, NOS

Genes involved and Proteins

Gene NameTPR
Location 3p26.1
Gene NameFGFR1
Location 8p11.23

Bibliography

Identification of a novel partner gene, TPR, fused to FGFR1 in 8p11 myeloproliferative syndrome
Li F, Zhai YP, Tang YM, Wang LP, Wan PJ
Genes Chromosomes Cancer 2012 Sep;51(9):890-7
PMID 22619110
 
Molecular identification of a TPR-FGFR1 fusion transcript in an adult with myeloproliferative neoplasm, T-lymphoblastic lymphoma, and a t(1;8)(q25;p11
Kim SY, Kim JE, Park S, Kim HK
2) Cancer Genet
PMID 25037443
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(1;8)(q31;p11) TPR/FGFR1

External links

TPR (1q31.1) FGFR1 (8p11.23)

Mitelman databaset(1;8)(q31;p11) [Case List]    t(1;8)(q31;p11) [Transloc-MCList] TPR/FGFR1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Mon Jul 9 10:13:06 CEST 2018


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