t(1;8)(q31;p11) TPR/FGFR1

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	1668
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Chronic myeloproliferative disorder, NOS

Genes involved and Proteins

Gene Name	TPR
Location	1q31.1

Gene Name	FGFR1
Location	8p11.23

Bibliography

Identification of a novel partner gene, TPR, fused to FGFR1 in 8p11 myeloproliferative syndrome

Li F, Zhai YP, Tang YM, Wang LP, Wan PJ

Genes Chromosomes Cancer 2012 Sep;51(9):890-7

PMID 22619110

Molecular identification of a TPR-FGFR1 fusion transcript in an adult with myeloproliferative neoplasm, T-lymphoblastic lymphoma, and a t(1;8)(q25;p11

Kim SY, Kim JE, Park S, Kim HK

2) Cancer Genet

PMID 25037443

Translocations implicated (Data extracted from papers in the Atlas)

	t(1;8)(q31;p11) TPR/FGFR1

External links

TPR (1q31.1) FGFR1 (8p11.23)

Mitelman database	t(1;8)(q31;p11) [Case List]    t(1;8)(q31;p11) [Transloc-MCList] TPR/FGFR1 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Tue Nov 6 14:04:52 CET 2018

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