| Identity |
| ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
| Atlas_Id | 1668 |
| Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute |
| Clinics and Pathology |
| Disease | Chronic myeloproliferative disorder, NOS |
| Genes involved and Proteins |
| Gene Name | TPR |
| Location | 1q31.1 |
| Gene Name | FGFR1 |
| Location | 8p11.23 |
| Bibliography |
| Identification of a novel partner gene, TPR, fused to FGFR1 in 8p11 myeloproliferative syndrome |
| Li F, Zhai YP, Tang YM, Wang LP, Wan PJ |
| Genes Chromosomes Cancer 2012 Sep;51(9):890-7 |
| PMID 22619110 |
| Molecular identification of a TPR-FGFR1 fusion transcript in an adult with myeloproliferative neoplasm, T-lymphoblastic lymphoma, and a t(1;8)(q25;p11 |
| Kim SY, Kim JE, Park S, Kim HK |
| 2) Cancer Genet |
| PMID 25037443 |
| Translocations implicated (Data extracted from papers in the Atlas) |
| t(1;8)(q31;p11) TPR/FGFR1 | |
| External links |
| Mitelman database | t(1;8)(q31;p11) |
| COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
| arrayMap (UZH-SIB Zurich) | [select an item] |
| REVIEW articles | automatic search in PubMed |
| Last year articles | automatic search in PubMed |
| All articles | automatic search in PubMed |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Fri Oct 8 16:37:53 CEST 2021 |
For comments and suggestions or contributions, please contact us