t(11;11)(p15;q23) NUP98/CADM1

Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	3035
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease

Acute megakaryoblastic leukemia (FAB type M7)

Genes involved and Proteins

Gene Name	NUP98
Location	11p15.4

Gene Name	CADM1
Location	11q23.3

Bibliography

Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes

de Rooij JD, Branstetter C, Ma J, Li Y, Walsh MP, Cheng J, Obulkasim A, Dang J, Easton J, Verboon LJ, Mulder HL, Zimmermann M, Koss C, Gupta P, Edmonson M, Rusch M, Lim JY, Reinhardt K, Pigazzi M, Song G, Yeoh AE, Shih LY, Liang DC, Halene S, Krause DS, Zhang J, Downing JR, Locatelli F, Reinhardt D, van den Heuvel-Eibrink MM, Zwaan CM, Fornerod M, Gruber TA

Nat Genet 2017 Mar;49(3):451-456

PMID 28112737

Translocations implicated (Data extracted from papers in the Atlas)

	t(11;11)(p15;q23) NUP98/CADM1

External links

NUP98 (11p15.4) CADM1 (11q23.3)

Mitelman database	t(11;11)(p15;q23) [Case List]    t(11;11)(p15;q23) [Transloc-MCList] NUP98/CADM1 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Wed Nov 28 16:23:04 CET 2018

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