CADM1 (cell adhesion molecule 1)

2003-02-01  

Identity

HGNC
CADM1
LOCATION
11q23.3
LOCUSID
23705
ALIAS
BL2,IGSF4,IGSF4A,NECL2,Necl-2,RA175,ST17,SYNCAM,TSLC1,sTSLC-1,sgIGSF,synCAM1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23705
MIM: 605686
HGNC: 5951
Ensembl: ENSG00000182985

Variants:

dbSNP: 23705
ClinVar: 23705
TCGA: ENSG00000182985
COSMIC: CADM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182985ENST00000331581Q9BY67
ENSG00000182985ENST00000331581X5D7A8
ENSG00000182985ENST00000452722Q9BY67
ENSG00000182985ENST00000452722X5D8W0
ENSG00000182985ENST00000536727X5DQS5
ENSG00000182985ENST00000537058Q9BY67
ENSG00000182985ENST00000537058X5DQR8
ENSG00000182985ENST00000540951F5H372
ENSG00000182985ENST00000542447Q9BY67
ENSG00000182985ENST00000542450F5H8J9
ENSG00000182985ENST00000543249H0YG94
ENSG00000182985ENST00000543540F5H0H5
ENSG00000182985ENST00000545094F5H125
ENSG00000182985ENST00000545380A0A0A0MTJ8
ENSG00000182985ENST00000612235A0A087X0T8
ENSG00000182985ENST00000616271A0A087X1W8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Cell adhesion molecules (CAMs)KEGGhsa04514
Cell-Cell communicationREACTOMER-HSA-1500931
Cell junction organizationREACTOMER-HSA-446728
Cell-cell junction organizationREACTOMER-HSA-421270
Adherens junctions interactionsREACTOMER-HSA-418990
Nectin/Necl trans heterodimerizationREACTOMER-HSA-420597

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369434322023Cell adhesion molecule 1 expression in mycosis fungoides versus parapsoriasis versus inflammatory dermatosis: an immunohistochemical comparative study.0
371663072023Interaction of the Hemagglutinin Stalk Region with Cell Adhesion Molecule (CADM) 1 and CADM2 Mediates the Spread between Neurons and Neuropathogenicity of Measles Virus with a Hyperfusogenic Fusion Protein.2
372911932023Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production.7
378142272023CADM1 impairs the effect of miR-1246 on promoting cell cycle progression in chemo-resistant leukemia cells.0
369434322023Cell adhesion molecule 1 expression in mycosis fungoides versus parapsoriasis versus inflammatory dermatosis: an immunohistochemical comparative study.0
371663072023Interaction of the Hemagglutinin Stalk Region with Cell Adhesion Molecule (CADM) 1 and CADM2 Mediates the Spread between Neurons and Neuropathogenicity of Measles Virus with a Hyperfusogenic Fusion Protein.2
372911932023Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production.7
378142272023CADM1 impairs the effect of miR-1246 on promoting cell cycle progression in chemo-resistant leukemia cells.0
346381302022The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11.1
347181692022Knockdown of long non-coding RNA LINC01006 represses the development of hepatocellular carcinoma by modulating the miR-194-5p/CADM1 axis.0
349748102022DNA hypermethylation of CADM1, PAX5, WT1, RARβ, and PAX6 genes in oropharyngeal cancer associated with human papillomavirus.2
351339832022Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes.4
365235932022Analysis of the key ligand receptor CADM1_CADM1 in the regulation of thyroid cancer based on scRNA-seq and bulk RNA-seq data.2
346381302022The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11.1
347181692022Knockdown of long non-coding RNA LINC01006 represses the development of hepatocellular carcinoma by modulating the miR-194-5p/CADM1 axis.0

Citation

Dessen P

CADM1 (cell adhesion molecule 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40936/cadm1-(cell-adhesion-molecule-1)