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t(11;12)(p15;q13) NUP98/RARG

Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 1600

Clinics and Pathology

Disease Acute promyelocytic leukemia (FAB type M3)

Genes involved and Proteins

Gene NameNUP98
Location 11p15.4
Gene NameRARG
Location 12q13.13

To be noted

Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on the chromosome abnormality, go to  How to contribute

Bibliography

A novel NUP98/RARG gene fusion in acute myeloid leukemia resembling acute promyelocytic leukemia
Such E, Cervera J, Valencia A, Barragán E, Ibañez M, Luna I, Fuster O, Perez-Sirvent ML, Senent L, Sempere A, Martinez J, Martín-Aragonés G, Sanz MA
Blood 2011 Jan 6;117(1):242-5
PMID 20935257
 


Translocations implicated (Data extracted from papers in the Atlas)

 t(11;12)(p15;q13) NUP98/RARG

External links

NUP98 (11p15.4) RARG (12q13.13)

Mitelman databaset(11;12)(p15;q13) [Case List]    t(11;12)(p15;q13) [Transloc-MCList] NUP98/RARG [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Wed Jan 10 17:22:34 CET 2018


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