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t(8;17)(q13;q23)

Written2009-01Jean-Loup Huret
Genetics, Dept Medical Information, University of Poitiers; CHU Poitiers Hospital, F-86021 Poitiers, France

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Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
ICD-Morpho 9975/3 Chronic myelogenous leukaemia, BCR-ABL1 positive; Myeloproliferative neoplasm, unclassifiable; Myelodysplastic/myeloproliferative neoplasm, unclassifiable
Atlas_Id 1403

Clinics and Pathology

Disease Chronic myelogenous leukaemia in transformation
Epidemiology Two cases available, a male patient and a female patient aged 50 years, with a 14 months survival (Swolin et al., 1983; Mashal et al., 1990).

Cytogenetics

Cytogenetics Morphological In each of the two cases, the t(8;17) accompanied the t(9;22)(q34;q11) translocation, or a variant. No other anomaly.

Genes involved and Proteins

Note The genes involved in the t(8;17) are unknown.

To be noted

Additional cases are needed to delineate the epidemiology of this rare entity:
you are welcome to submit a paper to our new Case Report section.

Bibliography

Rearrangement and expression of p53 in the chronic phase and blast crisis of chronic myelogenous leukemia.
Mashal R, Shtalrid M, Talpaz M, Kantarjian H, Smith L, Beran M, Cork A, Trujillo J, Gutterman J, Deisseroth A.
Blood. 1990 Jan 1;75(1):180-9.
PMID 1967214
 
Cytogenetic studies of bone marrow and extramedullary tissues and clinical course during metamorphosis of chronic myelocytic leukemia.
Swolin B, Weinfeld A, Waldenstrom J, Westin J.
Cancer Genet Cytogenet. 1983 Jul;9(3):197-209.
PMID 6574810
 

Citation

This paper should be referenced as such :
Huret, JL
t(8;17)(q13;q23)
Atlas Genet Cytogenet Oncol Haematol. 2009;13(12):980-980.
Free journal version : [ pdf ]   [ DOI ]
On line version : http://AtlasGeneticsOncology.org/Anomalies/t0817q13q23ID1403.html


Translocations implicated (Data extracted from papers in the Atlas)

 t(8;17)(q13;q23)

External links

Mitelman databaset(8;17)(q13;q23) [Case List]    t(8;17)(q13;q23) [Association List] Mitelman database (CGAP - NCBI)
arrayMapTopo ( C42) Morph ( 9975/3) - arrayMap (UZH-SIB Zurich)  [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(8;17)(q13;q23)
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


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indexed on : Fri Jun 30 11:23:29 CEST 2017


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