| Alias (NCBI) | CBFb |
| PEBP2b ( polyomavirus enhancer binding protein b) |
| HGNC (Hugo) |
CBFB |
| HGNC Alias symb | PEBP2B |
| HGNC Previous name | core-binding factor, beta subunit |
| core-binding factor beta subunit |
| LocusID (NCBI) |
865 |
| Atlas_Id |
45 |
| Location |
16q22.1 [Link to chromosome band 16q22] |
| Location_base_pair |
Starts at 67029149 and ends at 67101055 bp from pter ( according to GRCh38/hg38-Dec_2013) [Mapping CBFB.png] |
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| | CBFB (16q22) - Courtesy Mariano Rocchi, Resources for Molecular Cytogenetics. |
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| | CBFB (subunit b of core binding factor) Hybridization with LSI CBFB dual-color break part probe (Abbott Molecular, US), showing CBFB on 16q22.11 (red-green or a fused yellow signal) - Courtesy Adriana Zamecnikova. |
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| | ABL1 (9q34.12)::CBFB (16q22.1) | C16orf70 (16q22.1)::CBFB (16q22.1) | CBFB (16q22.1)::ATP13A3 (3q29) |
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CBFB (16q22.1)::CBFB (16q22.1) | CBFB (16q22.1)::CES4A (16q22.1) | CBFB (16q22.1)::FUK (16q22.1) |
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CBFB (16q22.1)::HNRNPA2B1 (7p15.2) | CBFB (16q22.1)::MRPL42 (12q22) | CBFB (16q22.1)::MUTYH (1p34.1) |
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CBFB (16q22.1)::MYH11 (16p13.11) | CBFB (16q22.1)::NAE1 (16q22.1) | CBFB (16q22.1)::NDE1 (16p13.11) |
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MYH11 (16p13.11)::CBFB (16q22.1) |
| Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11. |
| Castilla LH, Wijmenga C, Wang Q, Stacy T, Speck NA, Eckhaus M, Marín-Padilla M, Collins FS, Wynshaw-Boris A, Liu PP |
| Cell. 1996 ; 87 (4) : 687-696. |
| PMID 8929537 |
| |
| Identification of yeast artificial chromosomes containing the inversion 16 p-arm breakpoint associated with acute myelomonocytic leukemia. |
| Liu P, Claxton DF, Marlton P, Hajra A, Siciliano J, Freedman M, Chandrasekharappa SC, Yanagisawa K, Stallings RL, Collins FS |
| Blood. 1993 ; 82 (3) : 716-721. |
| PMID 8338941 |
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| Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha. |
| Ogawa E, Inuzuka M, Maruyama M, Satake M, Naito-Fujimoto M, Ito Y, Shigesada K |
| Virology. 1993 ; 194 (1) : 314-331. |
| PMID 8386878 |
| |
| PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene. |
| Ogawa E, Maruyama M, Kagoshima H, Inuzuka M, Lu J, Satake M, Shigesada K, Ito Y |
| Proceedings of the National Academy of Sciences of the United States of America. 1993 ; 90 (14) : 6859-6863. |
| PMID 8341710 |
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| The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo. |
| Wang Q, Stacy T, Miller JD, Lewis AF, Gu TL, Huang X, Bushweller JH, Bories JC, Alt FW, Ryan G, Liu PP, Wynshaw-Boris A, Binder M, Marín-Padilla M, Sharpe AH, Speck NA |
| Cell. 1996 ; 87 (4) : 697-708. |
| PMID 8929538 |
| |
| Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor. |
| Wang S, Wang Q, Crute BE, Melnikova IN, Keller SR, Speck NA |
| Molecular and cellular biology. 1993 ; 13 (6) : 3324-3339. |
| PMID 8497254 |
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| Acute myelogenous leukemia: a disorder of gene splicing? |
| van der Reijden BA, van Ommen GJ, Hagemeijer A, Breuning MH |
| Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 1996 ; 10 (2) : 204-206. |
| PMID 8637227 |
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