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ADGRG1 (adhesion G protein-coupled receptor G1)

Identity

Alias (NCBI)BFPP
BPPR
GPR56
TM7LN4
TM7XN1
HGNC (Hugo) ADGRG1
HGNC Alias symbTM7LN4
TM7XN1
HGNC Previous nameGPR56
HGNC Previous nameG protein-coupled receptor 56
LocusID (NCBI) 9289
Atlas_Id 40743
Location 16q21  [Link to chromosome band 16q21]
Location_base_pair Starts at 57628630 and ends at 57665567 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADAMTS10 (19p13.2) / ADGRG1 (16q21)ADGRG1 (16q21) / ADAMTS10 (19p13.2)ADGRG1 (16q21) / ADGRG1 (16q21)
CDKN1B (12p13.1) / ADGRG1 (16q21)ELN (7q11.23) / ADGRG1 (16q21)PBX1 (1q23.3) / ADGRG1 (16q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ADGRG1   4512
Cards
Entrez_Gene (NCBI)ADGRG1    adhesion G protein-coupled receptor G1
AliasesBFPP; BPPR; GPR56; TM7LN4; 
TM7XN1
GeneCards (Weizmann)ADGRG1
Ensembl hg19 (Hinxton)ENSG00000205336 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205336 [Gene_View]  ENSG00000205336 [Sequence]  chr16:57628630-57665567 [Contig_View]  ADGRG1 [Vega]
ICGC DataPortalENSG00000205336
TCGA cBioPortalADGRG1
AceView (NCBI)ADGRG1
Genatlas (Paris)ADGRG1
SOURCE (Princeton)ADGRG1
Genetics Home Reference (NIH)ADGRG1
Genomic and cartography
GoldenPath hg38 (UCSC)ADGRG1  -     chr16:57628630-57665567 +  16q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ADGRG1  -     16q21   [Description]    (hg19-Feb_2009)
GoldenPathADGRG1 - 16q21 [CytoView hg19]  ADGRG1 - 16q21 [CytoView hg38]
ImmunoBaseENSG00000205336
Genome Data Viewer NCBIADGRG1 [Mapview hg19]  
OMIM604110   606854   615752   
Gene and transcription
Genbank (Entrez)AF106858 AJ011001 AK074399 AK075270 AK075555
RefSeq transcript (Entrez)NM_001145770 NM_001145771 NM_001145772 NM_001145773 NM_001145774 NM_001290142 NM_001290143 NM_001290144 NM_001370428 NM_001370429 NM_001370430 NM_001370431 NM_001370432 NM_001370433 NM_001370434 NM_001370435 NM_001370436 NM_001370437 NM_001370438 NM_001370439 NM_001370440 NM_001370441 NM_001370442 NM_001370451 NM_001370453 NM_001370454 NM_005682 NM_201524 NM_201525
Consensus coding sequences : CCDS (NCBI)ADGRG1
Gene ExpressionADGRG1 [ NCBI-GEO ]   ADGRG1 [ EBI - ARRAY_EXPRESS ]   ADGRG1 [ SEEK ]   ADGRG1 [ MEM ]
Gene Expression Viewer (FireBrowse)ADGRG1 [ Firebrowse - Broad ]
GenevisibleExpression of ADGRG1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9289
GTEX Portal (Tissue expression)ADGRG1
Human Protein AtlasENSG00000205336-ADGRG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y653   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y653  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y653
PhosPhoSitePlusQ9Y653
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F2_4 (PS50261)    GPS (PS50221)   
Domains : Interpro (EBI)GAIN_A    GPCR_2-like    GPCR_2_secretin-like    GPR1/GPR3/GPR5    GPS    PLL   
Domain families : Pfam (Sanger)7tm_2 (PF00002)    GAIN_A (PF18619)    GPS (PF01825)    PLL (PF18587)   
Domain families : Pfam (NCBI)pfam00002    pfam18619    pfam01825    pfam18587   
Domain families : Smart (EMBL)GPS (SM00303)  
Conserved Domain (NCBI)ADGRG1
SuperfamilyQ9Y653
AlphaFold pdb e-kbQ9Y653   
Human Protein Atlas [tissue]ENSG00000205336-ADGRG1 [tissue]
HPRD06824
Protein Interaction databases
DIP (DOE-UCLA)Q9Y653
IntAct (EBI)Q9Y653
BioGRIDADGRG1
STRING (EMBL)ADGRG1
ZODIACADGRG1
Ontologies - Pathways
QuickGOQ9Y653
Ontology : AmiGOangiogenesis  G protein-coupled receptor activity  G protein-coupled receptor activity  protein binding  collagen binding  integral component of plasma membrane  cell adhesion  cell surface receptor signaling pathway  G protein-coupled receptor signaling pathway  adenylate cyclase-activating G protein-coupled receptor signaling pathway  Rho protein signal transduction  cell-cell signaling  brain development  heparin binding  heparin binding  negative regulation of cell population proliferation  vascular endothelial growth factor production  integral component of membrane  cell migration  cerebral cortex regionalization  cerebral cortex radial glia guided migration  layer formation in cerebral cortex  positive regulation of Rho protein signal transduction  membrane raft  positive regulation of cell adhesion  extracellular matrix binding  hematopoietic stem cell homeostasis  extracellular exosome  protein kinase C signaling  seminiferous tubule development  glial limiting end-foot  positive regulation of neural precursor cell proliferation  negative regulation of neuron migration  
Ontology : EGO-EBIangiogenesis  G protein-coupled receptor activity  G protein-coupled receptor activity  protein binding  collagen binding  integral component of plasma membrane  cell adhesion  cell surface receptor signaling pathway  G protein-coupled receptor signaling pathway  adenylate cyclase-activating G protein-coupled receptor signaling pathway  Rho protein signal transduction  cell-cell signaling  brain development  heparin binding  heparin binding  negative regulation of cell population proliferation  vascular endothelial growth factor production  integral component of membrane  cell migration  cerebral cortex regionalization  cerebral cortex radial glia guided migration  layer formation in cerebral cortex  positive regulation of Rho protein signal transduction  membrane raft  positive regulation of cell adhesion  extracellular matrix binding  hematopoietic stem cell homeostasis  extracellular exosome  protein kinase C signaling  seminiferous tubule development  glial limiting end-foot  positive regulation of neural precursor cell proliferation  negative regulation of neuron migration  
NDEx NetworkADGRG1
Atlas of Cancer Signalling NetworkADGRG1
Wikipedia pathwaysADGRG1
Orthology - Evolution
OrthoDB9289
GeneTree (enSembl)ENSG00000205336
Phylogenetic Trees/Animal Genes : TreeFamADGRG1
Homologs : HomoloGeneADGRG1
Homology/Alignments : Family Browser (UCSC)ADGRG1
Gene fusions - Rearrangements
Fusion : QuiverADGRG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerADGRG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADGRG1
dbVarADGRG1
ClinVarADGRG1
MonarchADGRG1
1000_GenomesADGRG1 
Exome Variant ServerADGRG1
GNOMAD BrowserENSG00000205336
Varsome BrowserADGRG1
ACMGADGRG1 variants
VarityQ9Y653
Genomic Variants (DGV)ADGRG1 [DGVbeta]
DECIPHERADGRG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisADGRG1 
Mutations
ICGC Data PortalADGRG1 
TCGA Data PortalADGRG1 
Broad Tumor PortalADGRG1
OASIS PortalADGRG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADGRG1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DADGRG1
Mutations and Diseases : HGMDADGRG1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaADGRG1
DgiDB (Drug Gene Interaction Database)ADGRG1
DoCM (Curated mutations)ADGRG1
CIViC (Clinical Interpretations of Variants in Cancer)ADGRG1
Cancer3DADGRG1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604110    606854    615752   
Orphanet13906    14781   
DisGeNETADGRG1
MedgenADGRG1
Genetic Testing Registry ADGRG1
NextProtQ9Y653 [Medical]
GENETestsADGRG1
Target ValidationADGRG1
Huge Navigator ADGRG1 [HugePedia]
ClinGenADGRG1
Clinical trials, drugs, therapy
MyCancerGenomeADGRG1
Protein Interactions : CTDADGRG1
Pharm GKB GenePA28901
PharosQ9Y653
Clinical trialADGRG1
Miscellaneous
canSAR (ICR)ADGRG1
HarmonizomeADGRG1
DataMed IndexADGRG1
Probes
Litterature
PubMed79 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXADGRG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:58:36 CEST 2021

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