Atlas of Genetics and Cytogenetics in Oncology and Haematology


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AMBP (alpha-1-microglobulin/bikunin precursor)

Identity

Alias_namesITI
ITIL
Alias_symbol (synonym)UTI
HCP
EDC1
HI30
IATIL
ITILC
Other aliasA1M
HGNC (Hugo) AMBP
LocusID (NCBI) 259
Atlas_Id 46052
Location 9q32  [Link to chromosome band 9q32]
Location_base_pair Starts at 114060128 and ends at 114078472 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AMBP   453
Cards
Entrez_Gene (NCBI)AMBP  259  alpha-1-microglobulin/bikunin precursor
AliasesA1M; EDC1; HCP; HI30; 
IATIL; ITI; ITIL; ITILC; UTI
GeneCards (Weizmann)AMBP
Ensembl hg19 (Hinxton)ENSG00000106927 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106927 [Gene_View]  chr9:114060128-114078472 [Contig_View]  AMBP [Vega]
ICGC DataPortalENSG00000106927
TCGA cBioPortalAMBP
AceView (NCBI)AMBP
Genatlas (Paris)AMBP
WikiGenes259
SOURCE (Princeton)AMBP
Genetics Home Reference (NIH)AMBP
Genomic and cartography
GoldenPath hg38 (UCSC)AMBP  -     chr9:114060128-114078472 -  9q32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AMBP  -     9q32   [Description]    (hg19-Feb_2009)
EnsemblAMBP - 9q32 [CytoView hg19]  AMBP - 9q32 [CytoView hg38]
Mapping of homologs : NCBIAMBP [Mapview hg19]  AMBP [Mapview hg38]
OMIM176870   
Gene and transcription
Genbank (Entrez)AK290837 AK303795 AK310776 AK310791 AY544123
RefSeq transcript (Entrez)NM_001633
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AMBP
Cluster EST : UnigeneHs.436911 [ NCBI ]
CGAP (NCI)Hs.436911
Alternative Splicing GalleryENSG00000106927
Gene ExpressionAMBP [ NCBI-GEO ]   AMBP [ EBI - ARRAY_EXPRESS ]   AMBP [ SEEK ]   AMBP [ MEM ]
Gene Expression Viewer (FireBrowse)AMBP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)259
GTEX Portal (Tissue expression)AMBP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02760   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02760  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02760
Splice isoforms : SwissVarP02760
PhosPhoSitePlusP02760
Domaine pattern : Prosite (Expaxy)BPTI_KUNITZ_1 (PS00280)    BPTI_KUNITZ_2 (PS50279)    LIPOCALIN (PS00213)   
Domains : Interpro (EBI)A1-microglobln    AMBP    Calycin    Calycin-like    Kunitz_BPTI    Lipocalin    Lipocalin_CS    Lipocln_cytosolic_FA-bd_dom    Prtase_inh_Kunz-CS   
Domain families : Pfam (Sanger)Kunitz_BPTI (PF00014)    Lipocalin (PF00061)   
Domain families : Pfam (NCBI)pfam00014    pfam00061   
Domain families : Smart (EMBL)KU (SM00131)  
Conserved Domain (NCBI)AMBP
DMDM Disease mutations259
Blocks (Seattle)AMBP
PDB (SRS)1BIK    3QKG    4ES7    4U30   
PDB (PDBSum)1BIK    3QKG    4ES7    4U30   
PDB (IMB)1BIK    3QKG    4ES7    4U30   
PDB (RSDB)1BIK    3QKG    4ES7    4U30   
Structural Biology KnowledgeBase1BIK    3QKG    4ES7    4U30   
SCOP (Structural Classification of Proteins)1BIK    3QKG    4ES7    4U30   
CATH (Classification of proteins structures)1BIK    3QKG    4ES7    4U30   
SuperfamilyP02760
Human Protein AtlasENSG00000106927
Peptide AtlasP02760
HPRD01467
IPIIPI00022426   IPI00922298   
Protein Interaction databases
DIP (DOE-UCLA)P02760
IntAct (EBI)P02760
FunCoupENSG00000106927
BioGRIDAMBP
STRING (EMBL)AMBP
ZODIACAMBP
Ontologies - Pathways
QuickGOP02760
Ontology : AmiGOserine-type endopeptidase inhibitor activity  protein binding  extracellular region  extracellular region  extracellular space  plasma membrane  receptor-mediated endocytosis  cell adhesion  female pregnancy  cell surface  negative regulation of endopeptidase activity  viral process  protein-chromophore linkage  calcium channel inhibitor activity  IgA binding  heme binding  protein catabolic process  small molecule binding  heme catabolic process  protein homodimerization activity  intracellular membrane-bounded organelle  negative regulation of JNK cascade  calcium oxalate binding  negative regulation of immune response  extracellular exosome  blood microparticle  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  protein binding  extracellular region  extracellular region  extracellular space  plasma membrane  receptor-mediated endocytosis  cell adhesion  female pregnancy  cell surface  negative regulation of endopeptidase activity  viral process  protein-chromophore linkage  calcium channel inhibitor activity  IgA binding  heme binding  protein catabolic process  small molecule binding  heme catabolic process  protein homodimerization activity  intracellular membrane-bounded organelle  negative regulation of JNK cascade  calcium oxalate binding  negative regulation of immune response  extracellular exosome  blood microparticle  
NDEx NetworkAMBP
Atlas of Cancer Signalling NetworkAMBP
Wikipedia pathwaysAMBP
Orthology - Evolution
OrthoDB259
GeneTree (enSembl)ENSG00000106927
Phylogenetic Trees/Animal Genes : TreeFamAMBP
HOVERGENP02760
HOGENOMP02760
Homologs : HomoloGeneAMBP
Homology/Alignments : Family Browser (UCSC)AMBP
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAMBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AMBP
dbVarAMBP
ClinVarAMBP
1000_GenomesAMBP 
Exome Variant ServerAMBP
ExAC (Exome Aggregation Consortium)AMBP (select the gene name)
Genetic variants : HAPMAP259
Genomic Variants (DGV)AMBP [DGVbeta]
DECIPHERAMBP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAMBP 
Mutations
ICGC Data PortalAMBP 
TCGA Data PortalAMBP 
Broad Tumor PortalAMBP
OASIS PortalAMBP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAMBP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAMBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AMBP
DgiDB (Drug Gene Interaction Database)AMBP
DoCM (Curated mutations)AMBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AMBP (select a term)
intoGenAMBP
Cancer3DAMBP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176870   
Orphanet
MedgenAMBP
Genetic Testing Registry AMBP
NextProtP02760 [Medical]
TSGene259
GENETestsAMBP
Target ValidationAMBP
Huge Navigator AMBP [HugePedia]
snp3D : Map Gene to Disease259
BioCentury BCIQAMBP
ClinGenAMBP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD259
Chemical/Pharm GKB GenePA24759
Clinical trialAMBP
Miscellaneous
canSAR (ICR)AMBP (select the gene name)
Probes
Litterature
PubMed112 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAMBP
EVEXAMBP
GoPubMedAMBP
iHOPAMBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:54:52 CEST 2017

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