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ANGPT4 (angiopoietin 4)

Identity

Other aliasANG3
ANG4
HGNC (Hugo) ANGPT4
LocusID (NCBI) 51378
Atlas_Id 638
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 853297 and ends at 896960 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ANGPT4   487
Cards
Entrez_Gene (NCBI)ANGPT4  51378  angiopoietin 4
AliasesANG3; ANG4
GeneCards (Weizmann)ANGPT4
Ensembl hg19 (Hinxton)ENSG00000101280 [Gene_View]  chr20:853297-896960 [Contig_View]  ANGPT4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000101280 [Gene_View]  chr20:853297-896960 [Contig_View]  ANGPT4 [Vega]
ICGC DataPortalENSG00000101280
TCGA cBioPortalANGPT4
AceView (NCBI)ANGPT4
Genatlas (Paris)ANGPT4
WikiGenes51378
SOURCE (Princeton)ANGPT4
Genetics Home Reference (NIH)ANGPT4
Genomic and cartography
GoldenPath hg19 (UCSC)ANGPT4  -     chr20:853297-896960 -  20p13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ANGPT4  -     20p13   [Description]    (hg38-Dec_2013)
EnsemblANGPT4 - 20p13 [CytoView hg19]  ANGPT4 - 20p13 [CytoView hg38]
Mapping of homologs : NCBIANGPT4 [Mapview hg19]  ANGPT4 [Mapview hg38]
OMIM603705   
Gene and transcription
Genbank (Entrez)AF074332 AF113708 AK304756 BC111922 BC111976
RefSeq transcript (Entrez)NM_001322809 NM_015985
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011387 NW_004929416
Consensus coding sequences : CCDS (NCBI)ANGPT4
Cluster EST : UnigeneHs.278973 [ NCBI ]
CGAP (NCI)Hs.278973
Alternative Splicing GalleryENSG00000101280
Gene ExpressionANGPT4 [ NCBI-GEO ]   ANGPT4 [ EBI - ARRAY_EXPRESS ]   ANGPT4 [ SEEK ]   ANGPT4 [ MEM ]
Gene Expression Viewer (FireBrowse)ANGPT4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51378
GTEX Portal (Tissue expression)ANGPT4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y264   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y264  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y264
Splice isoforms : SwissVarQ9Y264
PhosPhoSitePlusQ9Y264
Domaine pattern : Prosite (Expaxy)FIBRINOGEN_C_1 (PS00514)    FIBRINOGEN_C_2 (PS51406)   
Domains : Interpro (EBI)Ang-4    Fibrinogen_a/b/g_C_1    Fibrinogen_a/b/g_C_2    Fibrinogen_a/b/g_C_dom    Fibrinogen_CS   
Domain families : Pfam (Sanger)Fibrinogen_C (PF00147)   
Domain families : Pfam (NCBI)pfam00147   
Domain families : Smart (EMBL)FBG (SM00186)  
Conserved Domain (NCBI)ANGPT4
DMDM Disease mutations51378
Blocks (Seattle)ANGPT4
SuperfamilyQ9Y264
Human Protein AtlasENSG00000101280
Peptide AtlasQ9Y264
HPRD04747
IPIIPI00031775   IPI01012779   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y264
IntAct (EBI)Q9Y264
FunCoupENSG00000101280
BioGRIDANGPT4
STRING (EMBL)ANGPT4
ZODIACANGPT4
Ontologies - Pathways
QuickGOQ9Y264
Ontology : AmiGOangiogenesis  endothelial cell proliferation  extracellular region  extracellular space  activation of transmembrane receptor protein tyrosine kinase activity  Notch signaling pathway  positive regulation of endothelial cell migration  negative regulation of angiogenesis  transmembrane receptor protein tyrosine kinase activator activity  receptor tyrosine kinase binding  negative regulation of apoptotic process  positive regulation of blood vessel endothelial cell migration  negative regulation of blood vessel endothelial cell migration  positive regulation of angiogenesis  positive regulation of peptidyl-tyrosine phosphorylation  leukocyte migration  cellular response to hypoxia  
Ontology : EGO-EBIangiogenesis  endothelial cell proliferation  extracellular region  extracellular space  activation of transmembrane receptor protein tyrosine kinase activity  Notch signaling pathway  positive regulation of endothelial cell migration  negative regulation of angiogenesis  transmembrane receptor protein tyrosine kinase activator activity  receptor tyrosine kinase binding  negative regulation of apoptotic process  positive regulation of blood vessel endothelial cell migration  negative regulation of blood vessel endothelial cell migration  positive regulation of angiogenesis  positive regulation of peptidyl-tyrosine phosphorylation  leukocyte migration  cellular response to hypoxia  
Pathways : KEGGRas signaling pathway    Rap1 signaling pathway    HIF-1 signaling pathway    PI3K-Akt signaling pathway   
NDEx NetworkANGPT4
Atlas of Cancer Signalling NetworkANGPT4
Wikipedia pathwaysANGPT4
Orthology - Evolution
OrthoDB51378
GeneTree (enSembl)ENSG00000101280
Phylogenetic Trees/Animal Genes : TreeFamANGPT4
HOVERGENQ9Y264
HOGENOMQ9Y264
Homologs : HomoloGeneANGPT4
Homology/Alignments : Family Browser (UCSC)ANGPT4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANGPT4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANGPT4
dbVarANGPT4
ClinVarANGPT4
1000_GenomesANGPT4 
Exome Variant ServerANGPT4
ExAC (Exome Aggregation Consortium)ANGPT4 (select the gene name)
Genetic variants : HAPMAP51378
Genomic Variants (DGV)ANGPT4 [DGVbeta]
DECIPHER (Syndromes)20:853297-896960  ENSG00000101280
CONAN: Copy Number AnalysisANGPT4 
Mutations
ICGC Data PortalANGPT4 
TCGA Data PortalANGPT4 
Broad Tumor PortalANGPT4
OASIS PortalANGPT4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANGPT4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANGPT4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANGPT4
DgiDB (Drug Gene Interaction Database)ANGPT4
DoCM (Curated mutations)ANGPT4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANGPT4 (select a term)
intoGenANGPT4
Cancer3DANGPT4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603705   
Orphanet
MedgenANGPT4
Genetic Testing Registry ANGPT4
NextProtQ9Y264 [Medical]
TSGene51378
GENETestsANGPT4
Huge Navigator ANGPT4 [HugePedia]
snp3D : Map Gene to Disease51378
BioCentury BCIQANGPT4
ClinGenANGPT4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51378
Chemical/Pharm GKB GenePA24793
Clinical trialANGPT4
Miscellaneous
canSAR (ICR)ANGPT4 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANGPT4
EVEXANGPT4
GoPubMedANGPT4
iHOPANGPT4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:52:21 CEST 2017

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