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AP1M2 (adaptor related protein complex 1 mu 2 subunit)

Identity

Alias_namesadaptor-related protein complex 1, mu 2 subunit
adaptor-related protein complex 1 mu 2 subunit
Alias_symbol (synonym)HSMU1B
mu2
AP1-mu2
Other aliasMU-1B
MU1B
HGNC (Hugo) AP1M2
LocusID (NCBI) 10053
Atlas_Id 49850
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 10572671 and ends at 10587315 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AP1M2 (19p13.2) / AP1M2 (19p13.2)AP1M2 (19p13.2) / DTD1 (20p11.23)SRP68 (17q25.1) / AP1M2 (19p13.2)
SRP68 17q25.1 / AP1M2 19p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AP1M2   558
Cards
Entrez_Gene (NCBI)AP1M2  10053  adaptor related protein complex 1 mu 2 subunit
AliasesAP1-mu2; HSMU1B; MU-1B; MU1B; 
mu2
GeneCards (Weizmann)AP1M2
Ensembl hg19 (Hinxton)ENSG00000129354 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129354 [Gene_View]  chr19:10572671-10587315 [Contig_View]  AP1M2 [Vega]
ICGC DataPortalENSG00000129354
TCGA cBioPortalAP1M2
AceView (NCBI)AP1M2
Genatlas (Paris)AP1M2
WikiGenes10053
SOURCE (Princeton)AP1M2
Genetics Home Reference (NIH)AP1M2
Genomic and cartography
GoldenPath hg38 (UCSC)AP1M2  -     chr19:10572671-10587315 -  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AP1M2  -     19p13.2   [Description]    (hg19-Feb_2009)
EnsemblAP1M2 - 19p13.2 [CytoView hg19]  AP1M2 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBIAP1M2 [Mapview hg19]  AP1M2 [Mapview hg38]
OMIM607309   
Gene and transcription
Genbank (Entrez)AF020797 AK023863 AK222946 AK315689 AW370781
RefSeq transcript (Entrez)NM_001300887 NM_005498
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AP1M2
Cluster EST : UnigeneHs.18894 [ NCBI ]
CGAP (NCI)Hs.18894
Alternative Splicing GalleryENSG00000129354
Gene ExpressionAP1M2 [ NCBI-GEO ]   AP1M2 [ EBI - ARRAY_EXPRESS ]   AP1M2 [ SEEK ]   AP1M2 [ MEM ]
Gene Expression Viewer (FireBrowse)AP1M2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10053
GTEX Portal (Tissue expression)AP1M2
Human Protein AtlasENSG00000129354-AP1M2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6Q5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6Q5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6Q5
Splice isoforms : SwissVarQ9Y6Q5
PhosPhoSitePlusQ9Y6Q5
Domaine pattern : Prosite (Expaxy)CLAT_ADAPTOR_M_1 (PS00990)    CLAT_ADAPTOR_M_2 (PS00991)    MHD (PS51072)   
Domains : Interpro (EBI)AP_mu_sigma_su    Clathrin_mu    Clathrin_mu_CS    Longin-like_dom    MHD   
Domain families : Pfam (Sanger)Adap_comp_sub (PF00928)    Clat_adaptor_s (PF01217)   
Domain families : Pfam (NCBI)pfam00928    pfam01217   
Conserved Domain (NCBI)AP1M2
DMDM Disease mutations10053
Blocks (Seattle)AP1M2
SuperfamilyQ9Y6Q5
Human Protein Atlas [tissue]ENSG00000129354-AP1M2 [tissue]
Peptide AtlasQ9Y6Q5
HPRD06296
IPIIPI00002552   IPI00219794   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6Q5
IntAct (EBI)Q9Y6Q5
FunCoupENSG00000129354
BioGRIDAP1M2
STRING (EMBL)AP1M2
ZODIACAP1M2
Ontologies - Pathways
QuickGOQ9Y6Q5
Ontology : AmiGOGolgi membrane  protein binding  lysosomal membrane  cytosol  protein targeting  vesicle targeting  antigen processing and presentation of exogenous peptide antigen via MHC class II  clathrin adaptor complex  cytoplasmic vesicle membrane  clathrin-coated endocytic vesicle membrane  trans-Golgi network membrane  intracellular membrane-bounded organelle  regulation of defense response to virus by virus  
Ontology : EGO-EBIGolgi membrane  protein binding  lysosomal membrane  cytosol  protein targeting  vesicle targeting  antigen processing and presentation of exogenous peptide antigen via MHC class II  clathrin adaptor complex  cytoplasmic vesicle membrane  clathrin-coated endocytic vesicle membrane  trans-Golgi network membrane  intracellular membrane-bounded organelle  regulation of defense response to virus by virus  
Pathways : KEGGLysosome   
NDEx NetworkAP1M2
Atlas of Cancer Signalling NetworkAP1M2
Wikipedia pathwaysAP1M2
Orthology - Evolution
OrthoDB10053
GeneTree (enSembl)ENSG00000129354
Phylogenetic Trees/Animal Genes : TreeFamAP1M2
HOVERGENQ9Y6Q5
HOGENOMQ9Y6Q5
Homologs : HomoloGeneAP1M2
Homology/Alignments : Family Browser (UCSC)AP1M2
Gene fusions - Rearrangements
Fusion : MitelmanSRP68/AP1M2 [17q25.1/19p13.2]  [t(17;19)(q25;p13)]  
Fusion: TCGA_MDACCSRP68 17q25.1 AP1M2 19p13.2 GBM
Tumor Fusion PortalAP1M2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAP1M2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP1M2
dbVarAP1M2
ClinVarAP1M2
1000_GenomesAP1M2 
Exome Variant ServerAP1M2
ExAC (Exome Aggregation Consortium)ENSG00000129354
GNOMAD BrowserENSG00000129354
Genetic variants : HAPMAP10053
Genomic Variants (DGV)AP1M2 [DGVbeta]
DECIPHERAP1M2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAP1M2 
Mutations
ICGC Data PortalAP1M2 
TCGA Data PortalAP1M2 
Broad Tumor PortalAP1M2
OASIS PortalAP1M2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAP1M2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAP1M2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AP1M2
DgiDB (Drug Gene Interaction Database)AP1M2
DoCM (Curated mutations)AP1M2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AP1M2 (select a term)
intoGenAP1M2
Cancer3DAP1M2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607309   
Orphanet
DisGeNETAP1M2
MedgenAP1M2
Genetic Testing Registry AP1M2
NextProtQ9Y6Q5 [Medical]
TSGene10053
GENETestsAP1M2
Target ValidationAP1M2
Huge Navigator AP1M2 [HugePedia]
snp3D : Map Gene to Disease10053
BioCentury BCIQAP1M2
ClinGenAP1M2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10053
Chemical/Pharm GKB GenePA24849
Clinical trialAP1M2
Miscellaneous
canSAR (ICR)AP1M2 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAP1M2
EVEXAP1M2
GoPubMedAP1M2
iHOPAP1M2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:03:12 CET 2017

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