AP1M2 (adaptor related protein complex 1 subunit mu 2)

2007-12-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
AP1-mu2,HSMU1B,MU-1B,MU1B,mu2
FUSION GENES

Other Information

Locus ID:

NCBI: 10053
MIM: 607309
HGNC: 558
Ensembl: ENSG00000129354

Variants:

dbSNP: 10053
ClinVar: 10053
TCGA: ENSG00000129354
COSMIC: AP1M2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129354ENST00000250244Q9Y6Q5
ENSG00000129354ENST00000587069K7EL08
ENSG00000129354ENST00000589348K7EK69
ENSG00000129354ENST00000589571K7EPI9
ENSG00000129354ENST00000589684K7EPR4
ENSG00000129354ENST00000590923Q9Y6Q5
ENSG00000129354ENST00000591240K7EJJ1
ENSG00000129354ENST00000591676K7EMG5
ENSG00000129354ENST00000592285K7ERH5

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
LysosomeKEGGko04142
LysosomeKEGGhsa04142
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
Host Interactions of HIV factorsREACTOMER-HSA-162909
The role of Nef in HIV-1 replication and disease pathogenesisREACTOMER-HSA-164952
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adaptersREACTOMER-HSA-164938
Nef mediated downregulation of MHC class I complex cell surface expressionREACTOMER-HSA-164940
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
trans-Golgi Network Vesicle BuddingREACTOMER-HSA-199992
Clathrin derived vesicle buddingREACTOMER-HSA-421837
Golgi Associated Vesicle BiogenesisREACTOMER-HSA-432722
Lysosome Vesicle BiogenesisREACTOMER-HSA-432720

References

Pubmed IDYearTitleCitations
327597892020The MUDENG Augmentation: A Genesis in Anti-Cancer Therapy?6
327597892020The MUDENG Augmentation: A Genesis in Anti-Cancer Therapy?6
269086012016Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.63
269086012016Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.63
210480312011Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.5
210480312011Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.5
183563172008Caco-2 intestinal epithelial cells absorb soybean ferritin by mu2 (AP2)-dependent endocytosis.35
183563172008Caco-2 intestinal epithelial cells absorb soybean ferritin by mu2 (AP2)-dependent endocytosis.35
172618502007Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin.96
172618502007Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin.96
171458112006Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes.30
171458112006Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes.30
121340762002Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells.22
121340762002Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells.22

Citation

Dessen P

AP1M2 (adaptor related protein complex 1 subunit mu 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49850/ap1m2