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APP (amyloid beta precursor protein)

Identity

Alias (NCBI)AAA
ABETA
ABPP
AD1
APPI
CTFgamma
CVAP
PN-II
PN2
alpha-sAPP
preA4
HGNC (Hugo) APP
HGNC Alias symbalpha-sAPP
HGNC Alias namepeptidase nexin-II
HGNC Previous nameAD1
HGNC Previous nameAlzheimer disease
 amyloid beta (A4) precursor protein
LocusID (NCBI) 351
Atlas_Id 45541
Location 21q21.3  [Link to chromosome band 21q21]
Location_base_pair Starts at 25880550 and ends at 26170770 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ALB (4q13.3) / APP (21q21.3)APP (21q21.3) / APP (21q21.3)APP (21q21.3) / CCDC91 (12p11.22)
APP (21q21.3) / CYYR1 (21q21.3)APP (21q21.3) / EEA1 (12q22)APP (21q21.3) / FLOT1 (6p21.33)
APP (21q21.3) / MALAT1 (11q13.1)APP (21q21.3) / PDLIM3 (4q35.1)APP (21q21.3) / RAB11FIP1 (8p11.23)
APP (21q21.3) / RCAN1 (21q22.12)APP (21q21.3) / SEC63 (6q21)ATP5J (21q21.3) / APP (21q21.3)
CDYL (6p25.1) / APP (21q21.3)CLCN4 (Xp22.2) / APP (21q21.3)DAG1 (3p21.31) / APP (21q21.3)
ENO1 (1p36.23) / APP (21q21.3)HSP90B1 (12q23.3) / APP (21q21.3)SH3BGRL3 (1p36.11) / APP (21q21.3)
APP 21q21.3 / EEA1 12q22APP 21q21.3 / RCAN1 21q22.12APP 21q21.3 / SEC63 6q21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)APP   620
Cards
Entrez_Gene (NCBI)APP    amyloid beta precursor protein
AliasesAAA; ABETA; ABPP; AD1; 
APPI; CTFgamma; CVAP; PN-II; PN2; alpha-sAPP; preA4
GeneCards (Weizmann)APP
Ensembl hg19 (Hinxton)ENSG00000142192 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142192 [Gene_View]  ENSG00000142192 [Sequence]  chr21:25880550-26170770 [Contig_View]  APP [Vega]
ICGC DataPortalENSG00000142192
TCGA cBioPortalAPP
AceView (NCBI)APP
Genatlas (Paris)APP
SOURCE (Princeton)APP
Genetics Home Reference (NIH)APP
Genomic and cartography
GoldenPath hg38 (UCSC)APP  -     chr21:25880550-26170770 -  21q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APP  -     21q21.3   [Description]    (hg19-Feb_2009)
GoldenPathAPP - 21q21.3 [CytoView hg19]  APP - 21q21.3 [CytoView hg38]
ImmunoBaseENSG00000142192
Genome Data Viewer NCBIAPP [Mapview hg19]  
OMIM104300   104760   605714   
Gene and transcription
Genbank (Entrez)A02759 AB066441 AF282245 AK294534 AK295373
RefSeq transcript (Entrez)NM_000484 NM_001136016 NM_001136129 NM_001136130 NM_001136131 NM_001204301 NM_001204302 NM_001204303 NM_001385253 NM_201413 NM_201414
Consensus coding sequences : CCDS (NCBI)APP
Gene ExpressionAPP [ NCBI-GEO ]   APP [ EBI - ARRAY_EXPRESS ]   APP [ SEEK ]   APP [ MEM ]
Gene Expression Viewer (FireBrowse)APP [ Firebrowse - Broad ]
GenevisibleExpression of APP in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)351
GTEX Portal (Tissue expression)APP
Human Protein AtlasENSG00000142192-APP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)APP
Human Protein Atlas [tissue]ENSG00000142192-APP [tissue]
HPRD00100
Protein Interaction databases
BioGRIDAPP
STRING (EMBL)APP
ZODIACAPP
Ontologies - Pathways
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXAPP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:59:47 CEST 2021

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