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ARHGEF3 (Rho guanine nucleotide exchange factor 3)

Identity

Alias (NCBI)GEF3
STA3
XPLN
HGNC (Hugo) ARHGEF3
HGNC Alias symbSTA3
XPLN
GEF3
DKFZP434F2429
HGNC Alias nameexchange factor found in platelets and leukemic and neuronal tissues, XPLN
 RhoGEF protein
HGNC Previous nameRho guanine nucleotide exchange factor (GEF) 3
LocusID (NCBI) 50650
Atlas_Id 43151
Location 3p14.3  [Link to chromosome band 3p14]
Location_base_pair Starts at 56727420 and ends at 56801949 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARHGEF3 (3p14.3) / ACP6 (1q21.2)ARHGEF3 (3p14.3) / ANO10 (3p22.1)ARHGEF3 (3p14.3) / FDFT1 (8p23.1)
ARHGEF3 (3p14.3) / HESX1 (3p14.3)ARHGEF3 (3p14.3) / ILVBL (19p13.12)ARHGEF3 (3p14.3) / MALAT1 (11q13.1)
ARHGEF3 (3p14.3) / NDUFAF6 (8q22.1)ARHGEF3 (3p14.3) / RHAG (6p12.3)ARHGEF3 (3p14.3) / RPL23 (17q12)
ARHGEF3 (3p14.3) / SDC4 (20q13.12)ERC2 (3p14.3) / ARHGEF3 (3p14.3)PVT1 (8q24.21) / ARHGEF3 (3p14.3)
ARHGEF3 3p14.3 / ACP6 1q21.2ARHGEF3 3p14.3 / ANO10 3p22.1ARHGEF3 3p14.3 / FDFT1 8p23.1
ARHGEF3 3p14.3 / HESX1 3p14.3ARHGEF3 3p14.3 / RHAG 6p12.3ERC2 3p14.3 / ARHGEF3 3p14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)ARHGEF3   683
Cards
Entrez_Gene (NCBI)ARHGEF3    Rho guanine nucleotide exchange factor 3
AliasesGEF3; STA3; XPLN
GeneCards (Weizmann)ARHGEF3
Ensembl hg19 (Hinxton)ENSG00000163947 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163947 [Gene_View]  ENSG00000163947 [Sequence]  chr3:56727420-56801949 [Contig_View]  ARHGEF3 [Vega]
ICGC DataPortalENSG00000163947
TCGA cBioPortalARHGEF3
AceView (NCBI)ARHGEF3
Genatlas (Paris)ARHGEF3
SOURCE (Princeton)ARHGEF3
Genetics Home Reference (NIH)ARHGEF3
Genomic and cartography
GoldenPath hg38 (UCSC)ARHGEF3  -     chr3:56727420-56801949 -  3p14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARHGEF3  -     3p14.3   [Description]    (hg19-Feb_2009)
GoldenPathARHGEF3 - 3p14.3 [CytoView hg19]  ARHGEF3 - 3p14.3 [CytoView hg38]
ImmunoBaseENSG00000163947
genome Data Viewer NCBIARHGEF3 [Mapview hg19]  
OMIM612115   
Gene and transcription
Genbank (Entrez)AB209661 AF249744 AF433662 AK024340 AK225688
RefSeq transcript (Entrez)NM_001128615 NM_001128616 NM_001289698 NM_001377407 NM_001377408 NM_001377409 NM_001377410 NM_001377411 NM_001377412 NM_001377413 NM_001377414 NM_001377415 NM_019555
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARHGEF3
Alternative Splicing GalleryENSG00000163947
Gene ExpressionARHGEF3 [ NCBI-GEO ]   ARHGEF3 [ EBI - ARRAY_EXPRESS ]   ARHGEF3 [ SEEK ]   ARHGEF3 [ MEM ]
Gene Expression Viewer (FireBrowse)ARHGEF3 [ Firebrowse - Broad ]
GenevisibleExpression of ARHGEF3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50650
GTEX Portal (Tissue expression)ARHGEF3
Human Protein AtlasENSG00000163947-ARHGEF3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)ARHGEF3
Blocks (Seattle)ARHGEF3
Human Protein Atlas [tissue]ENSG00000163947-ARHGEF3 [tissue]
HPRD12480
IPIIPI00020949   IPI00385169   IPI00854602   IPI00946445   IPI00945383   IPI00791528   IPI00794649   IPI00792077   IPI00947543   IPI00981666   IPI00795793   IPI00944905   
Protein Interaction databases
BioGRIDARHGEF3
STRING (EMBL)ARHGEF3
ZODIACARHGEF3
Ontologies - Pathways
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXARHGEF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:11:34 CET 2021

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