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ARPC1B (actin related protein 2/3 complex subunit 1B)

Identity

Alias_namesactin related protein 2/3 complex, subunit 1B (41 kD)
actin related protein 2/3 complex subunit 1B, 41kDa
Alias_symbol (synonym)ARC41
p40-ARC
p41-ARC
Other alias
HGNC (Hugo) ARPC1B
LocusID (NCBI) 10095
Atlas_Id 46311
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 99374675 and ends at 99394781 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARPC1B (7q22.1) / ARPC1A (7q22.1)ARPC1B (7q22.1) / ARPC1B (7q22.1)ARPC1B (7q22.1) / DHX30 (3p21.31)
ARPC1B (7q22.1) / PDAP1 (7q22.1)TM9SF4 (20q11.21) / ARPC1B (7q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ARPC1B   704
Cards
Entrez_Gene (NCBI)ARPC1B  10095  actin related protein 2/3 complex subunit 1B
AliasesARC41; p40-ARC; p41-ARC
GeneCards (Weizmann)ARPC1B
Ensembl hg19 (Hinxton)ENSG00000130429 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130429 [Gene_View]  chr7:99374675-99394781 [Contig_View]  ARPC1B [Vega]
ICGC DataPortalENSG00000130429
TCGA cBioPortalARPC1B
AceView (NCBI)ARPC1B
Genatlas (Paris)ARPC1B
WikiGenes10095
SOURCE (Princeton)ARPC1B
Genetics Home Reference (NIH)ARPC1B
Genomic and cartography
GoldenPath hg38 (UCSC)ARPC1B  -     chr7:99374675-99394781 +  7q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ARPC1B  -     7q22.1   [Description]    (hg19-Feb_2009)
EnsemblARPC1B - 7q22.1 [CytoView hg19]  ARPC1B - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBIARPC1B [Mapview hg19]  ARPC1B [Mapview hg38]
OMIM604223   
Gene and transcription
Genbank (Entrez)AF006084 AK314818 AU143525 AY007111 BC002562
RefSeq transcript (Entrez)NM_005720
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ARPC1B
Cluster EST : UnigeneHs.489284 [ NCBI ]
CGAP (NCI)Hs.489284
Alternative Splicing GalleryENSG00000130429
Gene ExpressionARPC1B [ NCBI-GEO ]   ARPC1B [ EBI - ARRAY_EXPRESS ]   ARPC1B [ SEEK ]   ARPC1B [ MEM ]
Gene Expression Viewer (FireBrowse)ARPC1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10095
GTEX Portal (Tissue expression)ARPC1B
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15143   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15143  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15143
Splice isoforms : SwissVarO15143
PhosPhoSitePlusO15143
Domaine pattern : Prosite (Expaxy)WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)ARC1B    ARPC1    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)ARPC1B
DMDM Disease mutations10095
Blocks (Seattle)ARPC1B
SuperfamilyO15143
Human Protein AtlasENSG00000130429
Peptide AtlasO15143
HPRD10366
IPIIPI00005160   IPI00927861   IPI00927206   IPI00924861   IPI00927612   IPI00925248   IPI00924615   IPI00925033   
Protein Interaction databases
DIP (DOE-UCLA)O15143
IntAct (EBI)O15143
FunCoupENSG00000130429
BioGRIDARPC1B
STRING (EMBL)ARPC1B
ZODIACARPC1B
Ontologies - Pathways
QuickGOO15143
Ontology : AmiGOstructural constituent of cytoskeleton  cytosol  Arp2/3 protein complex  focal adhesion  movement of cell or subcellular component  actin cytoskeleton  response to estradiol  Arp2/3 complex-mediated actin nucleation  tubulobulbar complex  Fc-gamma receptor signaling pathway involved in phagocytosis  response to estrogen  ephrin receptor signaling pathway  actin filament binding  extracellular exosome  
Ontology : EGO-EBIstructural constituent of cytoskeleton  cytosol  Arp2/3 protein complex  focal adhesion  movement of cell or subcellular component  actin cytoskeleton  response to estradiol  Arp2/3 complex-mediated actin nucleation  tubulobulbar complex  Fc-gamma receptor signaling pathway involved in phagocytosis  response to estrogen  ephrin receptor signaling pathway  actin filament binding  extracellular exosome  
Pathways : KEGGFc gamma R-mediated phagocytosis    Regulation of actin cytoskeleton    Bacterial invasion of epithelial cells    Pathogenic Escherichia coli infection    Shigellosis    Salmonella infection   
NDEx NetworkARPC1B
Atlas of Cancer Signalling NetworkARPC1B
Wikipedia pathwaysARPC1B
Orthology - Evolution
OrthoDB10095
GeneTree (enSembl)ENSG00000130429
Phylogenetic Trees/Animal Genes : TreeFamARPC1B
HOVERGENO15143
HOGENOMO15143
Homologs : HomoloGeneARPC1B
Homology/Alignments : Family Browser (UCSC)ARPC1B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerARPC1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ARPC1B
dbVarARPC1B
ClinVarARPC1B
1000_GenomesARPC1B 
Exome Variant ServerARPC1B
ExAC (Exome Aggregation Consortium)ARPC1B (select the gene name)
Genetic variants : HAPMAP10095
Genomic Variants (DGV)ARPC1B [DGVbeta]
DECIPHERARPC1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisARPC1B 
Mutations
ICGC Data PortalARPC1B 
TCGA Data PortalARPC1B 
Broad Tumor PortalARPC1B
OASIS PortalARPC1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICARPC1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDARPC1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ARPC1B
DgiDB (Drug Gene Interaction Database)ARPC1B
DoCM (Curated mutations)ARPC1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ARPC1B (select a term)
intoGenARPC1B
Cancer3DARPC1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604223   
Orphanet
MedgenARPC1B
Genetic Testing Registry ARPC1B
NextProtO15143 [Medical]
TSGene10095
GENETestsARPC1B
Target ValidationARPC1B
Huge Navigator ARPC1B [HugePedia]
snp3D : Map Gene to Disease10095
BioCentury BCIQARPC1B
ClinGenARPC1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10095
Chemical/Pharm GKB GenePA24998
Clinical trialARPC1B
Miscellaneous
canSAR (ICR)ARPC1B (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineARPC1B
EVEXARPC1B
GoPubMedARPC1B
iHOPARPC1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:47:18 CEST 2017

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