Atlas of Genetics and Cytogenetics in Oncology and Haematology

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AS3MT (arsenite methyltransferase)

Identity

Alias_namesarsenic (? oxidation state) methyltransferase
Alias_symbol (synonym)CYT19
Other alias
HGNC (Hugo) AS3MT
LocusID (NCBI) 57412
Atlas_Id 50080
Location 10q24.32  [Link to chromosome band 10q24]
Location_base_pair Starts at 102869453 and ends at 102901898 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AS3MT (10q24.32) / GBF1 (10q24.32)RP11-548K23.11 () / AS3MT (10q24.32)AS3MT 10q24.32 / GBF1 10q24.32
RP11-548K23.11 AS3MT 10q24.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(10;10)(q24;q24) AS3MT/GBF1

External links

Nomenclature
HGNC (Hugo)AS3MT   17452
Cards
Entrez_Gene (NCBI)AS3MT  57412  arsenite methyltransferase
AliasesCYT19
GeneCards (Weizmann)AS3MT
Ensembl hg19 (Hinxton)ENSG00000214435 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000214435 [Gene_View]  chr10:102869453-102901898 [Contig_View]  AS3MT [Vega]
ICGC DataPortalENSG00000214435
TCGA cBioPortalAS3MT
AceView (NCBI)AS3MT
Genatlas (Paris)AS3MT
WikiGenes57412
SOURCE (Princeton)AS3MT
Genetics Home Reference (NIH)AS3MT
Genomic and cartography
GoldenPath hg38 (UCSC)AS3MT  -     chr10:102869453-102901898 +  10q24.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AS3MT  -     10q24.32   [Description]    (hg19-Feb_2009)
EnsemblAS3MT - 10q24.32 [CytoView hg19]  AS3MT - 10q24.32 [CytoView hg38]
Mapping of homologs : NCBIAS3MT [Mapview hg19]  AS3MT [Mapview hg38]
OMIM611806   
Gene and transcription
Genbank (Entrez)AF226730 AK057833 AK225972 AK309737 AW139845
RefSeq transcript (Entrez)NM_020682
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AS3MT
Cluster EST : UnigeneHs.720370 [ NCBI ]
CGAP (NCI)Hs.720370
Alternative Splicing GalleryENSG00000214435
Gene ExpressionAS3MT [ NCBI-GEO ]   AS3MT [ EBI - ARRAY_EXPRESS ]   AS3MT [ SEEK ]   AS3MT [ MEM ]
Gene Expression Viewer (FireBrowse)AS3MT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57412
GTEX Portal (Tissue expression)AS3MT
Human Protein AtlasENSG00000214435-AS3MT [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HBK9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HBK9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HBK9
Splice isoforms : SwissVarQ9HBK9
Catalytic activity : Enzyme2.1.1.137 [ Enzyme-Expasy ]   2.1.1.1372.1.1.137 [ IntEnz-EBI ]   2.1.1.137 [ BRENDA ]   2.1.1.137 [ KEGG ]   
PhosPhoSitePlusQ9HBK9
Domains : Interpro (EBI)Methyltranfer_dom    SAM-dependent_MTases   
Domain families : Pfam (Sanger)Methyltransf_31 (PF13847)   
Domain families : Pfam (NCBI)pfam13847   
Conserved Domain (NCBI)AS3MT
DMDM Disease mutations57412
Blocks (Seattle)AS3MT
SuperfamilyQ9HBK9
Human Protein Atlas [tissue]ENSG00000214435-AS3MT [tissue]
Peptide AtlasQ9HBK9
HPRD16511
IPIIPI00307524   
Protein Interaction databases
DIP (DOE-UCLA)Q9HBK9
IntAct (EBI)Q9HBK9
FunCoupENSG00000214435
BioGRIDAS3MT
STRING (EMBL)AS3MT
ZODIACAS3MT
Ontologies - Pathways
QuickGOQ9HBK9
Ontology : AmiGOmitochondrion  cytosol  cytosol  toxin metabolic process  arsonoacetate metabolic process  arsenite methyltransferase activity  arsenite methyltransferase activity  methylarsonite methyltransferase activity  methylation  
Ontology : EGO-EBImitochondrion  cytosol  cytosol  toxin metabolic process  arsonoacetate metabolic process  arsenite methyltransferase activity  arsenite methyltransferase activity  methylarsonite methyltransferase activity  methylation  
NDEx NetworkAS3MT
Atlas of Cancer Signalling NetworkAS3MT
Wikipedia pathwaysAS3MT
Orthology - Evolution
OrthoDB57412
GeneTree (enSembl)ENSG00000214435
Phylogenetic Trees/Animal Genes : TreeFamAS3MT
HOVERGENQ9HBK9
HOGENOMQ9HBK9
Homologs : HomoloGeneAS3MT
Homology/Alignments : Family Browser (UCSC)AS3MT
Gene fusions - Rearrangements
Fusion : MitelmanAS3MT/GBF1 [10q24.32/10q24.32]  
Fusion: TCGA_MDACCAS3MT 10q24.32 GBF1 10q24.32 LUAD
Fusion: TCGA_MDACCRP11-548K23.11 AS3MT 10q24.32 PRAD
Fusion PortalAS3MT 10q24.32 GBF1 10q24.32 LUAD
Fusion PortalRP11-548K23.11 AS3MT 10q24.32 PRAD
Fusion : QuiverAS3MT
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAS3MT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AS3MT
dbVarAS3MT
ClinVarAS3MT
1000_GenomesAS3MT 
Exome Variant ServerAS3MT
ExAC (Exome Aggregation Consortium)ENSG00000214435
GNOMAD BrowserENSG00000214435
Genetic variants : HAPMAP57412
Genomic Variants (DGV)AS3MT [DGVbeta]
DECIPHERAS3MT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAS3MT 
Mutations
ICGC Data PortalAS3MT 
TCGA Data PortalAS3MT 
Broad Tumor PortalAS3MT
OASIS PortalAS3MT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAS3MT  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAS3MT
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch AS3MT
DgiDB (Drug Gene Interaction Database)AS3MT
DoCM (Curated mutations)AS3MT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AS3MT (select a term)
intoGenAS3MT
Cancer3DAS3MT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611806   
Orphanet
DisGeNETAS3MT
MedgenAS3MT
Genetic Testing Registry AS3MT
NextProtQ9HBK9 [Medical]
TSGene57412
GENETestsAS3MT
Target ValidationAS3MT
Huge Navigator AS3MT [HugePedia]
snp3D : Map Gene to Disease57412
BioCentury BCIQAS3MT
ClinGenAS3MT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57412
Chemical/Pharm GKB GenePA134896392
Clinical trialAS3MT
Miscellaneous
canSAR (ICR)AS3MT (select the gene name)
Probes
Litterature
PubMed80 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAS3MT
EVEXAS3MT
GoPubMedAS3MT
iHOPAS3MT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jun 18 19:10:11 CEST 2018
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