ATP8B1 (ATPase, class I, type 8B, member 1)

Identity

Other names	ATPIC
	BRIC
	FIC1
	PFIC
	PFIC1
HGNC	ATP8B1
Location	18q21-q22|18q21.31
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ATP8B1   3706
Entrez_Gene	ATP8B1  5205  ATPase, class I, type 8B, member 1
	Cards
GeneCards	ATP8B1
Ensembl	ATP8B1 [Search_View]   ENSG00000081923 [Gene_View]
Genatlas	ATP8B1
GeneLynx	ATP8B1
eGenome	ATP8B1
euGene	5205
	Genomic and cartography
GoldenPath	ATP8B1  -     chr18:53464657-53550037 -  18q21.31   [Description]    (hg18-March_2006)
Ensembl	ATP8B1 - 18q21.31 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ATP8B1
	Gene and transcription
Genbank	AF032442 [ ENTREZ ]
Genbank	AF038007 [ ENTREZ ]
Genbank	AK128536 [ ENTREZ ]
Genbank	BC003534 [ ENTREZ ]
RefSeq	NM_005603 [ SRS ]    NM_005603 [ ENTREZ ]
RefSeq	AC_000061 [ SRS ]    AC_000061 [ ENTREZ ]
RefSeq	AC_000150 [ SRS ]    AC_000150 [ ENTREZ ]
RefSeq	NC_000018 [ SRS ]    NC_000018 [ ENTREZ ]
RefSeq	NG_007148 [ SRS ]    NG_007148 [ ENTREZ ]
RefSeq	NT_025028 [ SRS ]    NT_025028 [ ENTREZ ]
RefSeq	NW_001838469 [ SRS ]    NW_001838469 [ ENTREZ ]
RefSeq	NW_927106 [ SRS ]    NW_927106 [ ENTREZ ]
AceView	ATP8B1 AceView - NCBI
Unigene	Hs.216623 [ SRS ]    Hs.216623 [ NCBI ]     HS216623 [ spliceNest ]
Fast-db	4866 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O43520 [ SRS]    O43520 [ EXPASY ]     O43520 [ INTERPRO ]     O43520 [ UNIPROT ]
Prosite	PS00154 ATPASE_E1_E2 [ SRS ]    PS00154 ATPASE_E1_E2 [ Expasy ]
Interpro	IPR001757 ATPase_P [ SRS ]    IPR001757 ATPase_P [ EBI ]
Interpro	IPR006539 Flippase [ SRS ]    IPR006539 Flippase [ EBI ]
CluSTr	O43520
Blocks	O43520
HPRD	03867
	Protein Interaction databases
DIP	O43520
IntAct	O43520
	Polymorphism : SNP, mutations, diseases
OMIM	211600;243300;602397    [ map ]
GENECLINICS	211600;243300;602397
SNP	ATP8B1 [dbSNP-NCBI]
SNP	NM_005603 [SNP-NCI]
SNP	ATP8B1 [GeneSNPs - Utah]  ATP8B1] [HGBASE - SRS]
HAPMAP	ATP8B1 [HAPMAP]
HGMD	ATP8B1
	General knowledge
Family Browser	ATP8B1 [UCSC Family Browser]
SOURCE	NM_005603
SMD	Hs.216623
SAGE	Hs.216623
Enzyme	3.6.3.1 [ Enzyme-Expasy ]   3.6.3.1 [ Enzyme-SRS ]   3.6.3.1 [ IntEnz-EBI ]   3.6.3.1 [ BRENDA ]   3.6.3.1 [ KEGG ]   3.6.3.1 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	phospholipid-translocating ATPase activity [Amigo]  phospholipid-translocating ATPase activity
GO	ATP binding [Amigo]  ATP binding
GO	membrane fraction [Amigo]  membrane fraction
GO	integral to plasma membrane [Amigo]  integral to plasma membrane
GO	transport [Amigo]  transport
GO	bile acid metabolic process [Amigo]  bile acid metabolic process
GO	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [Amigo]  ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
GO	bile acid and bile salt transport [Amigo]  bile acid and bile salt transport
GO	phospholipid transport [Amigo]  phospholipid transport
GO	membrane [Amigo]  membrane
GO	apical plasma membrane [Amigo]  apical plasma membrane
GO	negative regulation of transcription [Amigo]  negative regulation of transcription
GO	hydrolase activity [Amigo]  hydrolase activity
GO	ATPase activity [Amigo]  ATPase activity
PubGene	ATP8B1
TreeFam	ATP8B1
CTD	5205 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ATP8B1 Related clones (RZPD - Berlin)
	PubMed
PubMed	19 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:01:22 2008