Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

BDKRB1 (bradykinin receptor B1)

Identity

Alias_symbol (synonym)BKR1
B1BKR
bradyb1
Other aliasB1R
BDKRB2
BKB1R
BRADYB1
HGNC (Hugo) BDKRB1
LocusID (NCBI) 623
Atlas_Id 46143
Location 14q32.2  [Link to chromosome band 14q32]
Location_base_pair Starts at 96256210 and ends at 96264763 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BDKRB1   1029
Cards
Entrez_Gene (NCBI)BDKRB1  623  bradykinin receptor B1
AliasesB1BKR; B1R; BDKRB2; BKB1R; 
BKR1; BRADYB1
GeneCards (Weizmann)BDKRB1
Ensembl hg19 (Hinxton)ENSG00000100739 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100739 [Gene_View]  chr14:96256210-96264763 [Contig_View]  BDKRB1 [Vega]
ICGC DataPortalENSG00000100739
TCGA cBioPortalBDKRB1
AceView (NCBI)BDKRB1
Genatlas (Paris)BDKRB1
WikiGenes623
SOURCE (Princeton)BDKRB1
Genetics Home Reference (NIH)BDKRB1
Genomic and cartography
GoldenPath hg38 (UCSC)BDKRB1  -     chr14:96256210-96264763 +  14q32.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BDKRB1  -     14q32.2   [Description]    (hg19-Feb_2009)
EnsemblBDKRB1 - 14q32.2 [CytoView hg19]  BDKRB1 - 14q32.2 [CytoView hg38]
Mapping of homologs : NCBIBDKRB1 [Mapview hg19]  BDKRB1 [Mapview hg38]
OMIM600337   
Gene and transcription
Genbank (Entrez)AF117819 AJ238044 AK291970 AK309528 BC034705
RefSeq transcript (Entrez)NM_000710
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BDKRB1
Cluster EST : UnigeneHs.525572 [ NCBI ]
CGAP (NCI)Hs.525572
Alternative Splicing GalleryENSG00000100739
Gene ExpressionBDKRB1 [ NCBI-GEO ]   BDKRB1 [ EBI - ARRAY_EXPRESS ]   BDKRB1 [ SEEK ]   BDKRB1 [ MEM ]
Gene Expression Viewer (FireBrowse)BDKRB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)623
GTEX Portal (Tissue expression)BDKRB1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP46663   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP46663  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP46663
Splice isoforms : SwissVarP46663
PhosPhoSitePlusP46663
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Brdyknn_1_rcpt    Brdyknn_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)BDKRB1
DMDM Disease mutations623
Blocks (Seattle)BDKRB1
SuperfamilyP46663
Human Protein AtlasENSG00000100739
Peptide AtlasP46663
HPRD02639
IPIIPI00296538   IPI01024843   
Protein Interaction databases
DIP (DOE-UCLA)P46663
IntAct (EBI)P46663
FunCoupENSG00000100739
BioGRIDBDKRB1
STRING (EMBL)BDKRB1
ZODIACBDKRB1
Ontologies - Pathways
QuickGOP46663
Ontology : AmiGOnegative regulation of protein phosphorylation  positive regulation of leukocyte migration  bradykinin receptor activity  protein binding  endoplasmic reticulum  plasma membrane  integral component of plasma membrane  inflammatory response  positive regulation of cytosolic calcium ion concentration  protein kinase C-activating G-protein coupled receptor signaling pathway  response to mechanical stimulus  cell migration  sensory perception of pain  negative regulation of cell growth  response to lipopolysaccharide  peptide binding  neuron projection  negative regulation of blood pressure  positive regulation of release of sequestered calcium ion into cytosol  
Ontology : EGO-EBInegative regulation of protein phosphorylation  positive regulation of leukocyte migration  bradykinin receptor activity  protein binding  endoplasmic reticulum  plasma membrane  integral component of plasma membrane  inflammatory response  positive regulation of cytosolic calcium ion concentration  protein kinase C-activating G-protein coupled receptor signaling pathway  response to mechanical stimulus  cell migration  sensory perception of pain  negative regulation of cell growth  response to lipopolysaccharide  peptide binding  neuron projection  negative regulation of blood pressure  positive regulation of release of sequestered calcium ion into cytosol  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction    Complement and coagulation cascades    Regulation of actin cytoskeleton   
NDEx NetworkBDKRB1
Atlas of Cancer Signalling NetworkBDKRB1
Wikipedia pathwaysBDKRB1
Orthology - Evolution
OrthoDB623
GeneTree (enSembl)ENSG00000100739
Phylogenetic Trees/Animal Genes : TreeFamBDKRB1
HOVERGENP46663
HOGENOMP46663
Homologs : HomoloGeneBDKRB1
Homology/Alignments : Family Browser (UCSC)BDKRB1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBDKRB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BDKRB1
dbVarBDKRB1
ClinVarBDKRB1
1000_GenomesBDKRB1 
Exome Variant ServerBDKRB1
ExAC (Exome Aggregation Consortium)BDKRB1 (select the gene name)
Genetic variants : HAPMAP623
Genomic Variants (DGV)BDKRB1 [DGVbeta]
DECIPHERBDKRB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBDKRB1 
Mutations
ICGC Data PortalBDKRB1 
TCGA Data PortalBDKRB1 
Broad Tumor PortalBDKRB1
OASIS PortalBDKRB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBDKRB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBDKRB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BDKRB1
DgiDB (Drug Gene Interaction Database)BDKRB1
DoCM (Curated mutations)BDKRB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BDKRB1 (select a term)
intoGenBDKRB1
Cancer3DBDKRB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600337   
Orphanet
MedgenBDKRB1
Genetic Testing Registry BDKRB1
NextProtP46663 [Medical]
TSGene623
GENETestsBDKRB1
Target ValidationBDKRB1
Huge Navigator BDKRB1 [HugePedia]
snp3D : Map Gene to Disease623
BioCentury BCIQBDKRB1
ClinGenBDKRB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD623
Chemical/Pharm GKB GenePA79
Clinical trialBDKRB1
Miscellaneous
canSAR (ICR)BDKRB1 (select the gene name)
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBDKRB1
EVEXBDKRB1
GoPubMedBDKRB1
iHOPBDKRB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:25:27 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.