BRI3 (brain protein I3)

2009-05-01  

Identity

HGNC
LOCATION
7q21.3
LOCUSID
ALIAS
I3
FUSION GENES

Other Information

Locus ID:

NCBI: 25798
MIM: 615628
HGNC: 1109
Ensembl: ENSG00000164713

Variants:

dbSNP: 25798
ClinVar: 25798
TCGA: ENSG00000164713
COSMIC: BRI3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164713ENST00000297290O95415
ENSG00000164713ENST00000491463I3L1V6
ENSG00000164713ENST00000539286F5GXW6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
173900492007A gene signature of 8 genes could identify the risk of recurrence and progression in Dukes' B colon cancer patients.24
193666922009BRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2.19
205380552010Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets.9
165080922005Crystallization and preliminary X-ray analysis of the GST-fused human Bri3 N-terminal domain.1
184526482008BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells.0

Citation

Dessen P

BRI3 (brain protein I3)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50886/bri3